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[抗抑郁药对缺氧耐受性和体育锻炼的影响]

[Effects of antidepressive agents on tolerance of hypoxia and physical exercise].

作者信息

Andreeva N I, Golovina S M, Parshin V A, Mashkovskiĭ M D

出版信息

Biull Eksp Biol Med. 1991 Aug;112(8):156-8.

PMID:1786375
Abstract

In experiments on mice and rats we studied the influence of antidepressants on hypoxic and physical tolerance. The antidepressants pyrazidol, azaphen, imipramine and moclobemide as well as the nootropic drug piracetam prolonged the life of animals in conditions of hypoxic and hemic hypoxia and increased the survival rate of rats in circulatory hypoxia. In experiments on mice antidepressants increased also the time of swimming.

摘要

在对小鼠和大鼠进行的实验中,我们研究了抗抑郁药对缺氧耐受性和身体耐力的影响。抗抑郁药吡唑醇、阿扎芬、丙咪嗪和吗氯贝胺以及益智药吡拉西坦,可延长动物在低氧和血液性缺氧条件下的存活时间,并提高大鼠在循环性缺氧中的存活率。在对小鼠进行的实验中,抗抑郁药还延长了其游泳时间。

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