Bull World Health Organ. 1991;69(6):657-66.
Visual loss or disability from cataract represents a massive public health and socioeconomic problem in most developing countries. At present, some 13.5 million cases require treatment and this number will increase, as most countries in the Third World are unable to cope with both the backlog and new cases. Cataract extraction with intraocular lens (IOL) implantation is now the established and preferred method in industrialized countries. The introduction of IOLs in developing countries, however, depends on their having adequately trained manpower and facilities (equipment and supplies, including IOLs) for surgery. This will inevitably increase the cost per operated case which, despite the scarce resources for cataract surgery in many developing countries, may be justified by the improved restoration of the patient's vision. Experience has led to the following generic designs for IOLs: the one-piece or three-piece C-loop polymethylmethacrylate (PMMA) posterior chamber lens, which is the current favourite; and, the flexible or rigid one-piece all-PMMA anterior chamber lens, which is a valid alternative in many situations. Further scientific evaluation of the use of these lenses in a wide variety of settings in developing countries is required. Operations research is also needed in order better to define and standardize the various steps and procedures in the surgical and post-operative management of IOL implantation in Third World settings. Meanwhile, the following should be available to ensure safe and good quality cataract surgery using IOLs in developing countries: properly trained surgeons; the needed facilities and equipment with regular supplies; a good quality lens of appropriate design; and the necessary means for careful follow-up of operated patients.
在大多数发展中国家,白内障导致的视力丧失或残疾是一个重大的公共卫生和社会经济问题。目前,约有1350万例白内障患者需要治疗,而且这个数字还会增加,因为大多数第三世界国家既无法处理积压病例,也无法应对新增病例。在工业化国家,白内障摘除联合人工晶状体(IOL)植入术现已成为既定的首选方法。然而,在发展中国家引入人工晶状体,取决于这些国家是否拥有受过充分培训的人力以及手术所需的设施(设备和物资,包括人工晶状体)。这将不可避免地增加每例手术的成本,尽管许多发展中国家用于白内障手术的资源稀缺,但患者视力恢复的改善或许能证明成本增加是合理的。经验促使人工晶状体出现了以下通用设计:一体式或三件式C形袢聚甲基丙烯酸甲酯(PMMA)后房型人工晶状体,这是目前最受欢迎的;以及柔性或刚性一体式全PMMA前房型人工晶状体,在许多情况下它是一种有效的替代选择。需要在发展中国家的各种环境中对这些人工晶状体的使用进行进一步的科学评估。还需要进行运筹学研究,以便更好地界定和规范第三世界国家人工晶状体植入手术及术后管理的各个步骤和程序。与此同时,为确保在发展中国家使用人工晶状体进行安全且高质量的白内障手术,应具备以下条件:训练有素的外科医生;配备定期供应物资的所需设施和设备;设计合适的优质人工晶状体;以及对手术患者进行仔细随访的必要手段。