Ashraf Tariq, Rasool Syed Ishtiaq, Saghir Tahir, Rizvi Syed Nadeem Hassan, Qamar Nadeem, Zaman Khan Shah, Ishaque Mohammad, Kundi Asadullah
Catheterization Laboratory, National Institute of Cardiovascular Diseases, Karachi.
J Pak Med Assoc. 2007 Jul;57(7):359-62.
To evaluate the impact of Export Aspiration Catheter with restoration of ECG changes, arterial flow and myocardial perfusion in patients with ST segment elevation Myocardial Infarction undergoing Percutaneous Coronary Intervention (PCI).
A total of 40 consecutive patients with ST Segment Elevation Myocardial Infarction (STEMI) were selected. They underwent treatment according to the surgeon's discretion to either standard PCI or PCI with thrombus aspiration Catheter. Primary end points of the study were ST Segment resolution (STR) > 70% and myocardial blush grade (MBG) > 2.
The base line clinical and procedural characteristics were same for both the groups. In the post intervention comparison the thrombus aspiration group was found to have significantly better outcomes as compared to the standard PCI group with regards to TIMI flow grade (p = 0.009) and myocardial blush grade (p = 0.001). Considering the criteria for MBG and STR together, the thrombus aspiration was found to have significantly better outcome than the standard PCI group (p = 0.017).
This non-randomized study shows that Export Aspiration Catheter group with STEMI undergoing primary PCI is feasible and results in better angiographic ECG and myocardial perfusion rates compared with standard PCI. Role of export catheter in rescue PCI and thrombus Sapheneous Venous Graft (SVG) as primary PCI is questionable and needs larger randomized studies to prove its efficacy.
评估出口抽吸导管对接受经皮冠状动脉介入治疗（PCI）的ST段抬高型心肌梗死患者心电图变化恢复、动脉血流及心肌灌注的影响。
共选取40例连续的ST段抬高型心肌梗死（STEMI）患者。他们根据外科医生的判断接受标准PCI或使用血栓抽吸导管的PCI治疗。该研究的主要终点为ST段回落（STR）>70%和心肌 blush分级（MBG）>2。
两组的基线临床和操作特征相同。在干预后比较中，发现血栓抽吸组在TIMI血流分级（p = 0.009）和心肌 blush分级（p = 0.001）方面与标准PCI组相比有显著更好的结果。综合考虑MBG和STR的标准，发现血栓抽吸组的结果明显优于标准PCI组（p = 0.017）。
这项非随机研究表明，对于接受直接PCI的STEMI患者，出口抽吸导管组是可行的，与标准PCI相比，其血管造影心电图和心肌灌注率更好。出口导管在补救性PCI以及作为直接PCI的大隐静脉桥血管（SVG）血栓方面的作用存在疑问，需要更大规模的随机研究来证明其疗效。
