Terui Keita, Koshimichi Sinichiro, Nakao Naoyuki, Uematsu Yuji, Itakura Toru
Department of Neurosurgery, Hidaka General Hospital.
No Shinkei Geka. 2007 Sep;35(9):895-9.
Whereas fibrous dysplasia is a well-known, developmental skeletal disorder with a benign clinical course, fibrous dysplasia of the clivus is extremely rare and has seldom been reported. Differentiating this benign entity from more aggressive diseases involving the clivus is important for the proper management of lesions in this area. We here report a case of fibrous dysplasia of the clivus and discuss its radiographic features. The patient was 55-year-old male who had suffered from headache for months. Physical and neurological examinations found no abnormalities. The computed tomographic (CT) scan and magnetic resonance imaging (MRI) showed an abnormal mass lesion in the lower of the third clivus. On CT scan, the mass lesion exhibited a ground-glass appearance. The lesion was detected as hypointense and a mixture of hyperintense and isointense areas on T1-weighted and T2-weighted MRI, respectively. Heterogenous enhancement was noted after infusion of GD-DTPA. The patient underwent a transsphenoidal resection of the mass and the histopathologic diagnosis was fibrous dysplasia.
骨纤维异常增殖症是一种众所周知的、具有良性临床病程的发育性骨骼疾病，而斜坡骨纤维异常增殖症极为罕见，鲜有报道。将这种良性病变与累及斜坡的更具侵袭性的疾病区分开来，对于正确处理该区域的病变很重要。我们在此报告一例斜坡骨纤维异常增殖症病例，并讨论其影像学特征。患者为一名55岁男性，数月来一直头痛。体格检查和神经检查未发现异常。计算机断层扫描（CT）和磁共振成像（MRI）显示斜坡下部有一异常肿块病变。CT扫描显示，肿块病变呈磨玻璃样外观。在T1加权和T2加权MRI上，该病变分别表现为低信号以及高信号和等信号区域的混合。注入钆喷酸葡胺（GD-DTPA）后可见不均匀强化。患者接受了经蝶窦肿块切除术，组织病理学诊断为骨纤维异常增殖症。
