Jóźwik Maciej, Jóźwik Marcin, Bartnicki Janusz, Jóźwik Michał
Klinika Ginekologii Akademii Medycznej w Białymstoku.
Ginekol Pol. 2007 May;78(5):405-10.
The aim of this review was to present recent information about the fetal condition in cases of intrahepatic cholestasis of pregnancy. A relatively mild course of maternal disease does not predict fetal well-being accurately. Increased risk of sudden intrauterine death was emphasized, implicating the need for more stringent obstetric monitoring of fetal condition in this disorder. A pathogenetic mechanism leading to sudden deterioration of fetal wellbeing was proposed and discussed. Current recommendations regarding medical management of intrahepatic cholestasis of pregnancy were also presented.
本综述的目的是介绍妊娠肝内胆汁淤积症病例中有关胎儿状况的最新信息。母体疾病相对较轻的病程并不能准确预测胎儿的健康状况。强调了宫内猝死风险增加，这意味着在这种疾病中需要对胎儿状况进行更严格的产科监测。提出并讨论了导致胎儿健康突然恶化的发病机制。还介绍了目前关于妊娠肝内胆汁淤积症药物治疗的建议。
