Calleja Subirán M C, Hernández Gutiérrez F J, López Elzaurdia C, Revestido García R
Servicios de Medicina Interna, Cirugía y Anatomía Patológica, Hospital Nuestra Senora de Sonsoles, Avila, Spain.
An Med Interna. 2007 Apr;24(4):179-84. doi: 10.4321/s0212-71992007000400006.
The liposarcoma is a malignant tumor of mesodermic origin derived of the adipose tissue. Liposarcoma s types, according to his histological diagnosis, are: mixoide, pleomorphic, well differentiated and dedifferentiated. It can get to reach enormous proportions, mainly when it is located at abdominal level. His treatment is the radical surgery, it is possible, together with radiation therapy and/or chemotherapy. Four patients diagnosed of liposarcoma are shown up, a case of liposarcoma well differentiated, another case of liposarcoma pleomorphic and two cases about liposarcoma mixoide; with the characteristic that one of these two cases presented a local recidivation with a dediferenciation of itself. The evolution of the four cases, was in a different way. So, their prognosis is going to depend on their histopathologic variety and on a possible multicentricidad that is going to difficult the complete radical surgical exeresis.
脂肪肉瘤是一种起源于中胚层的恶性肿瘤,由脂肪组织衍生而来。根据组织学诊断,脂肪肉瘤的类型有:黏液样、多形性、高分化和去分化。它可以长得非常大,主要是当它位于腹部时。其治疗方法是根治性手术,也可以结合放疗和/或化疗。展示了4例诊断为脂肪肉瘤的患者,1例高分化脂肪肉瘤,1例多形性脂肪肉瘤,2例黏液样脂肪肉瘤;其中2例中的1例出现局部复发并伴有自身去分化。这4例患者的病情发展各不相同。因此,它们的预后将取决于其组织病理学类型以及可能存在的多中心性,这会使根治性手术切除变得困难。