Reiter Alexander M, Schwarz Tobias
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
J Am Vet Med Assoc. 2007 Sep 15;231(6):924-30. doi: 10.2460/javma.231.6.924.
To document computed tomography (CT) features in dogs with masticatory myositis.
Retrospective case series.
7 dogs with an immunologic diagnosis of masticatory myositis and an absence of clinical abnormalities of any skeletal muscles other than the masticatory muscles.
History; clinical, hematologic, biochemical, immunologic, cytologic, and histologic findings; and pre- and postcontrast CT imaging features of masticatory muscles and head and neck lymph nodes were extracted from medical records.
On CT images, changes in size (atrophy or swelling) were common for all masticatory muscles except the digastricus muscles, which were involved only in 1 dog. Pre-contrast attenuation changes, most often hypoattenuation with varied distribution patterns, were seen in masticatory muscles of 4 dogs. Contrast enhancement with a predominantly inhomogeneous distribution pattern was seen in the temporalis, masseter, and pterygoid muscles of all dogs. Head and neck lymph nodes were enlarged in all but 1 dog and had contrast enhancement with predominantly central or homogeneous distribution patterns. Muscle biopsy was performed in 6 dogs, with biopsy specimens obtained from areas that had the most obvious contrast enhancement on CT images. For all 6 dogs, biopsy specimens had histologic features indicative of masticatory myositis.
Results suggested that CT may be a useful adjunct in the diagnosis of masticatory myositis in dogs, including selection of sites for diagnostic muscle biopsy.
记录患咀嚼肌炎犬的计算机断层扫描(CT)特征。
回顾性病例系列研究。
7只经免疫诊断为咀嚼肌炎且除咀嚼肌外任何骨骼肌均无临床异常的犬。
从病历中提取病史、临床、血液学、生物化学、免疫学、细胞学和组织学检查结果,以及咀嚼肌和头颈部淋巴结的对比剂增强前后CT影像特征。
在CT图像上,除二腹肌外,所有咀嚼肌均常见大小改变(萎缩或肿胀),仅1只犬的二腹肌受累。4只犬的咀嚼肌可见对比剂增强前的密度改变,最常见的是低密度,分布模式多样。所有犬的颞肌、咬肌和翼状肌均可见对比剂增强,主要呈不均匀分布模式。除1只犬外,所有犬的头颈部淋巴结均肿大,且对比剂增强主要呈中央或均匀分布模式。对6只犬进行了肌肉活检,活检标本取自CT图像上对比剂增强最明显的区域。所有6只犬的活检标本均具有提示咀嚼肌炎的组织学特征。
结果表明,CT可能是诊断犬咀嚼肌炎的有用辅助手段,包括选择诊断性肌肉活检的部位。