视交叉的耐受性如何？视野检查与神经影像学的相关性。
How robust is the optic chiasm? Perimetric and neuro-imaging correlations.
作者信息
Frisén L, Jensen C
机构信息
Institute of Neuroscience and Physiology, Section of Neurological Sciences and Rehabilitation, and Institute of Clinical Sciences, Section of Radiology, The Sahlgrenska Academy, Göteborg University, Sweden.
出版信息
Acta Neurol Scand. 2008 Mar;117(3):198-204. doi: 10.1111/j.1600-0404.2007.00927.x. Epub 2007 Sep 12.
OBJECTIVES
Analysis of form and function relationships with tumour-mediated dislocations and deformations of the optic chiasm.
MATERIALS AND METHODS
Results of magnetic resonance tomography and two forms of quantitative, computerized perimetry were contrasted in 31 patients with pituitary adenomata impinging on the chiasm, prior to treatment.
RESULTS
Perimetric abnormalities ranged from none to modest. High-pass Resolution Perimetry (HRP) produced abnormal results in 10 cases and RareBit perimetry (RBP) in 15 cases. Overall, field defects and qualitative stages of deformation and dislocation of the chiasm were well correlated. Among quantitative indices, the best correlations were obtained by a measure of the cranio-caudal position of the chiasm.
CONCLUSIONS
On average, an elevation of the chiasm by 6 mm will be associated with abnormal visual fields in 50% of the cases. An additional elevation of 5 mm will raise the incidence of field defects to 90%.
目的
分析视交叉肿瘤介导的脱位和变形的形态与功能关系。
材料与方法
对31例治疗前因垂体腺瘤压迫视交叉的患者的磁共振断层扫描结果和两种形式的定量计算机视野检查结果进行对比。
结果
视野异常程度从无到中度不等。高通分辨率视野检查（HRP）在10例中出现异常结果，RareBit视野检查（RBP）在15例中出现异常结果。总体而言，视野缺损与视交叉变形和脱位的定性阶段相关性良好。在定量指标中，通过测量视交叉的颅尾位置获得了最佳相关性。
结论
平均而言，视交叉抬高6mm在50%的病例中会伴有异常视野。再额外抬高5mm会使视野缺损的发生率升至90%。
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