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德国南部冷血马四肢关节骨软骨病患病率的遗传参数

Genetic parameters for the prevalence of osteochondrosis in the limb joints of South German Coldblood horses.

作者信息

Wittwer C, Hamann H, Rosenberger E, Distl O

机构信息

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover, Hannover, Germany.

出版信息

J Anim Breed Genet. 2007 Oct;124(5):302-7. doi: 10.1111/j.1439-0388.2007.00670.x.

DOI:10.1111/j.1439-0388.2007.00670.x
PMID:17868083
Abstract

Heritabilities were estimated for osteochondrosis (OC) in fetlock and hock joints and palmar/plantar osseous fragments in fetlock joints of South German Coldblood (SGC) horses using Residual Maximum Likelihood (REML) under a linear animal model. The analyses were based on the results of a standardized radiographic examination of 167 SGC horses with a mean age of 14 months. The heritabilities linearly estimated and transformed onto the liability scale were for OC in fetlock joints 0.16 and for OC in hock joints 0.04. Considering fetlock and hock OC together, results in a heritability of 0.17. Palmar/plantar osseus fragments of the fetlock joints showed a heritability of 0.48. We concluded that there is most likely a genetic component in the variation of the development of osteochondrosis in fetlock and hock joints as well as for palmar/plantar osseus fragments of fetlock joints of the investigated population of SGC horses.

摘要

在一个线性动物模型下,使用残差最大似然法(REML)估计了德国南部冷血(SGC)马的跗关节和飞节的骨软骨病(OC)以及跗关节掌/跖骨碎片的遗传力。分析基于对167匹平均年龄为14个月的SGC马进行标准化X线检查的结果。线性估计并转换到易感性尺度上的遗传力,跗关节OC为0.16,飞节OC为0.04。将跗关节和飞节OC综合考虑,遗传力为0.17。跗关节掌/跖骨碎片的遗传力为0.48。我们得出结论,在所研究的SGC马群体中,跗关节和飞节骨软骨病的发展变化以及跗关节掌/跖骨碎片很可能存在遗传成分。

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