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[单次静脉注射塞米翁对初发性动脉粥样硬化性脑病患者脑循环动力学及脑功能活动的影响]

[The dynamics of the cerebral circulation and of brain functional activity in patients with initial atherosclerotic encephalopathy under the influence of a single intravenous administration of sermion].

作者信息

Mints A Ia, Karaban' I N, Litvinenko A A

出版信息

Farmakol Toksikol. 1991 Jul-Aug;54(4):59-62.

PMID:1786832
Abstract

The efficacy of sermion was studied in 41 patients of the middle and elderly ages. The reactive changes in the parameters of the cerebral circulation (the frontomastoidal RhEG), total hemodynamics, frequency-integration characteristics of EEG and visual evoked potentials at the administration of 2 mg and 4 mg of sermion were shown. There are given recommendations for the differential approach to the choice of the drug doses in the elderly persons taking into consideration the parameters of the background reactivity of the CNS and the state of vascular regulation.

摘要

对41例中老年患者研究了喜得镇的疗效。研究显示,给予2毫克和4毫克喜得镇后,脑循环参数(额乳突电阻抗容积描记法)、全血流动力学、脑电图频率积分特征及视觉诱发电位出现了反应性变化。考虑到中枢神经系统背景反应性参数和血管调节状态,给出了针对老年人选择药物剂量的差异化方法建议。

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