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创伤性后尿道断裂的尿道重建:25年经验的结果

Urethral reconstruction for traumatic posterior urethral disruption: outcomes of a 25-year experience.

作者信息

Cooperberg Matthew R, McAninch Jack W, Alsikafi Nejd F, Elliott Sean P

机构信息

Department of Urology, University of California, San Francisco, San Francisco, California 94143, USA.

出版信息

J Urol. 2007 Nov;178(5):2006-10; discussion 2010. doi: 10.1016/j.juro.2007.07.020. Epub 2007 Sep 17.

Abstract

PURPOSE

Management of posterior urethral disruption due to pelvic trauma can be quite challenging and is the subject of ongoing controversy. This study presents an update of the University of California, San Francisco experience with delayed anastomotic posterior urethroplasty for management of these injuries.

MATERIALS AND METHODS

Since 1979 all patients undergoing posterior urethroplasty by a single surgeon at University of California, San Francisco and its affiliated hospitals have been entered prospectively into a patient registry. For this cohort descriptive statistics were calculated and recurrence was analyzed with the Kaplan-Meier method. Success was defined as no recurrence (by symptoms and/or retrograde urethrogram) or a mild recurrence managed successfully with a single internal urethrotomy.

RESULTS

A total of 134 male patients were analyzed with a mean of 32.9 and a median of 12 months followup. Mean patient age at surgery was 34.8 years. Of the patients 35% had undergone at least 1 prior procedure for stricture including prior urethroplasty in 16%. In addition, 22% required partial pubectomy and 4% a combined abdominal-perineal approach with total pubectomy. Of patients with a closed bladder neck on urethrography 34% vs 7% of those with an open bladder neck required pubectomy (p <0.001). Stricture length tended to be longer in pubectomy cases (mean 3.2 vs 2.1 cm by urethrography, p = 0.055). Of the patients 14% experienced recurrent stricture at a mean of 12 months, 42% of whom were treated successfully with a single urethrotomy. The overall success rate allowing 1 direct vision internal urethrotomy was 93%.

CONCLUSIONS

Anastomotic urethroplasty offers excellent long-term results to patients with posterior urethral trauma and stricture disease even after multiple prior procedures.

摘要

目的

骨盆创伤所致后尿道断裂的处理颇具挑战性,且一直存在争议。本研究介绍了加利福尼亚大学旧金山分校在延迟吻合性后尿道成形术治疗此类损伤方面的最新经验。

材料与方法

自1979年以来,在加利福尼亚大学旧金山分校及其附属医院由同一外科医生实施后尿道成形术的所有患者均被前瞻性纳入患者登记系统。对该队列进行描述性统计,并采用Kaplan-Meier法分析复发情况。成功定义为无复发(根据症状和/或逆行尿道造影)或经单次尿道内切开术成功处理的轻度复发。

结果

共分析了134例男性患者,平均随访时间为32.9个月,中位随访时间为12个月。手术时患者的平均年龄为34.8岁。35%的患者此前至少接受过1次治疗狭窄的手术,其中16%曾接受过尿道成形术。此外,22%的患者需要行部分耻骨切除术,4%的患者需要采用经腹会阴联合入路并进行全耻骨切除术。尿道造影显示膀胱颈闭合的患者中,34%需要行耻骨切除术,而膀胱颈开放的患者中这一比例为7%(p<0.001)。耻骨切除术病例的狭窄长度往往更长(尿道造影显示平均为3.2 cm,而未行耻骨切除术的患者平均为2.1 cm,p = 0.055)。14%的患者出现复发性狭窄,平均发生时间为12个月,其中42%经单次尿道内切开术成功治疗。允许进行1次直视下尿道内切开术的总体成功率为93%。

结论

即使在多次先前手术之后,吻合性尿道成形术仍能为后尿道创伤和狭窄疾病患者提供出色的长期疗效。

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