Carrie C, Pommier P
Département de Radiothérapie, Centre Léon-Bérard, 28, rue Laënnec, 69008, Lyon, France.
Cancer Radiother. 2007 Nov;11(6-7):370-2. doi: 10.1016/j.canrad.2007.08.001. Epub 2007 Sep 14.
Salvage radiotherapy after radical prostatectomy can be delivered either in case of biochemical recurrence or in situation of clinical relapse. In this last case, results are poor regarding disease-free survival but quite interesting regarding the local control rate. The best situation for salvage radiotherapy is still the rising PSA case: half of the patients can be in complete remission at 5 years after 65 Gy radiotherapy. The role of hormone therapy combined with salvage radiotherapy is still under investigation.
前列腺癌根治术后的挽救性放疗可在生化复发或临床复发的情况下进行。在后一种情况下,无病生存率的结果较差,但局部控制率方面相当可观。挽救性放疗的最佳情况仍是前列腺特异抗原(PSA)升高的病例:65Gy放疗后,一半患者在5年后可完全缓解。激素治疗联合挽救性放疗的作用仍在研究中。