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表现为溃疡性扁桃体肿物伴同侧淋巴结病的梅毒性扁桃体炎。

Syphilitic tonsillitis presenting as an ulcerated tonsillar tumor with ipsilateral lymphadenopathy.

作者信息

Oddó David, Carrasco Gonzalo, Capdeville Felipe, Ayala María Fernanda

机构信息

Department of Anatomic Pathology, Pontificia Universidad Católica de Chile, 8320000 Santiago de Chile.

出版信息

Ann Diagn Pathol. 2007 Oct;11(5):353-7. doi: 10.1016/j.anndiagpath.2006.04.002. Epub 2007 Jul 24.

Abstract

We describe a 49-year-old man who presented with a cervical mass of a week's evolution, which clinically mimicked a tumoral expansion. Physical examination showed a left cervical mass of 6 x 4 x 2 cm, associated to a left ulcerated tonsillar tumor. The presumptive diagnosis was a tonsillar cancer with lymph node involvement. An amygdalectomy and a frozen section biopsy of the cervical tumor were performed. The biopsy displayed a reactive lymphadenopathy with follicular and interfollicular hyperplasia rich in plasma cells, epithelioid areas, and an outstanding parcel fibrosis of subcapsular, interfollicular, and perifollicular distribution associated to an isolated focus of polymorphonuclear leukocytes and obliterative parietal angiovascular proliferation. The tonsil presented a similar but ulcerated process. These results suggested an infectious reactive process, probably luetic. A Warthin-Starry stain revealed spirochetes in the tonsillar ulcer. Laboratory examinations revealed a positive VDRL test and negative serology for HIV. In conclusion, a primary syphilis of the oropharyngeal tonsil with a syphilic lymphadenopathy was diagnosed. The literature about tonsillar syphilis is reviewed.

摘要

我们描述了一名49岁男性,其颈部肿块已有一周发展过程,临床上类似肿瘤性扩张。体格检查发现左侧颈部有一个6×4×2厘米的肿块,伴有左侧扁桃体肿瘤溃疡。初步诊断为扁桃体癌伴淋巴结受累。进行了扁桃体切除术及颈部肿瘤冰冻切片活检。活检显示为反应性淋巴结病,伴有富含浆细胞的滤泡和滤泡间增生、上皮样区域,以及包膜下、滤泡间和滤泡周围分布的显著束状纤维化,伴有孤立的多形核白细胞聚集和闭塞性血管壁增生。扁桃体呈现类似但有溃疡的病变。这些结果提示为感染性反应过程,可能为梅毒。Warthin-Starry染色显示扁桃体溃疡中有螺旋体。实验室检查显示性病研究实验室试验(VDRL)阳性,HIV血清学阴性。总之,诊断为口咽扁桃体原发性梅毒伴梅毒淋巴结病。本文对有关扁桃体梅毒的文献进行了综述。

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