Samaras Menelaos G, Panagoulis Evangelos, Kotanidis Christakis, Karamagkiolas Sotirios, Foukas Periklis G
Second Department of Pathology, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, GRC.
Second Otolaryngology Department, National and Kapodistrian University of Athens, "Attikon" University Hospital, Athens, GRC.
Cureus. 2025 Mar 29;17(3):e81407. doi: 10.7759/cureus.81407. eCollection 2025 Mar.
This case report describes the clinical presentation, diagnosis, and management of a 52-year-old Greek male with unilateral tonsillar swelling and concomitant syphilis, emphasizing the key histopathological differentials. The patient presented with a longstanding unilateral right tonsillar enlargement, and further evaluation revealed syphilis as the underlying disease. The management included intramuscular penicillin therapy and close follow-up with dermatology and otolaryngology specialists. This report aims to raise awareness among healthcare providers, particularly pathologists, about considering tonsillar syphilis in the differential diagnosis of tonsillar abnormalities, especially in patients at increased risk for syphilis infection.
本病例报告描述了一名52岁希腊男性单侧扁桃体肿胀并伴有梅毒的临床表现、诊断及治疗，着重强调关键的组织病理学鉴别要点。该患者长期存在右侧单侧扁桃体肿大，进一步检查发现梅毒是潜在病因。治疗包括肌肉注射青霉素，并由皮肤科和耳鼻喉科专家密切随访。本报告旨在提高医疗服务提供者，尤其是病理学家，对扁桃体梅毒在扁桃体异常鉴别诊断中的认识，特别是在梅毒感染风险增加的患者中。
