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输尿管镜检查是小儿结石病的一线治疗方法吗?

Is ureteroscopy first line treatment for pediatric stone disease?

作者信息

Smaldone Marc C, Cannon Glenn M, Wu Hsi-Yang, Bassett Jeffrey, Polsky Ethan G, Bellinger Mark F, Docimo Steven G, Schneck Francis X

机构信息

Division of Pediatric Urology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213-3232, USA.

出版信息

J Urol. 2007 Nov;178(5):2128-31; discussion 2131. doi: 10.1016/j.juro.2007.07.050. Epub 2007 Sep 17.

Abstract

PURPOSE

We report our current outcomes for ureteroscopic management of pediatric stone disease.

MATERIALS AND METHODS

We carried out a retrospective review of all ureteroscopic procedures for kidney or ureteral calculi performed between 2001 and 2005. Stone location and size, preoperative and postoperative stenting, intraoperative dilation, use of ureteral access sheath, stone-free rates and complications were noted.

RESULTS

A total of 100 patients (58% female, mean age 13.2 years) underwent 115 procedures. Stones were located in the renal pelvis in 6% of patients, upper pole in 10%, mid ureter in 11%, lower pole in 17%, proximal ureter in 19% and distal ureter in 37%. Mean stone size was 8.3 mm (median 7.0), with a mean of 1.5 stones per patient. Preoperative stenting was used in 54% of patients, and a stent was placed postoperatively in 76%. Ureteral coaxial dilators and ureteral access sheaths were used in 70% and 24% of patients, respectively. There were no major intraoperative complications, although 5 patients required stent placement for ureteral perforation or extravasation. One patient had a ureteral stricture requiring ureteral reimplantation. Mean followup was 10.1 months (median 2.6). Stone-free rate was 91% on followup ultrasound, abdominal radiography or computerized tomography. Seven patients required staged ureteroscopic procedures to achieve stone-free status. While the number of percutaneous nephrolithotomy and shock wave lithotripsy cases remained stable, the number of ureteroscopic cases increased 7-fold during this period.

CONCLUSIONS

Improved ureteroscopic access to stones throughout the pediatric urinary tract and stone-free rates that are comparable to the adult population have led to the adoption of ureteroscopy as first line therapy in children at our institution.

摘要

目的

我们报告目前小儿结石病输尿管镜治疗的结果。

材料与方法

我们对2001年至2005年间所有因肾或输尿管结石而行输尿管镜手术的病例进行了回顾性研究。记录结石的位置和大小、术前和术后支架置入情况、术中扩张情况、输尿管通路鞘的使用情况、结石清除率及并发症。

结果

共有100例患者(58%为女性,平均年龄13.2岁)接受了115次手术。结石位于肾盂的患者占6%,上极占10%,输尿管中段占11%,下极占17%,输尿管近端占19%,输尿管远端占37%。平均结石大小为8.3mm(中位数7.0),每位患者平均有1.5块结石。54%的患者术前放置了支架,76%的患者术后放置了支架。分别有70%和24%的患者使用了输尿管同轴扩张器和输尿管通路鞘。术中无严重并发症,尽管有5例患者因输尿管穿孔或外渗需要放置支架。1例患者出现输尿管狭窄,需要行输尿管再植术。平均随访时间为10.1个月(中位数2.6)。随访超声、腹部X线平片或计算机断层扫描显示结石清除率为91%。7例患者需要分期行输尿管镜手术以达到结石清除状态。在此期间,经皮肾镜取石术和冲击波碎石术的病例数保持稳定,而输尿管镜手术的病例数增加了7倍。

结论

小儿尿路结石输尿管镜取石术的改进以及与成人相当的结石清除率,促使我们机构将输尿管镜检查作为儿童的一线治疗方法。

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