Harte D B, Manly R S
J Dent Res. 1976 May-Jun;55(3):322-7. doi: 10.1177/00220345760550030601.
A five-factor study was done on human dentin abrasion that involved two abrasives, either alone or in dentifrice form, two brush brands, two brush hardnesses, two concentrations, and two temperatures of testing. The hard brushes caused 3.6 times as much wear as the soft brushes, a greater influence than the abrasives compared. A brush X hardness interaction indicated that there is a wide variation among the stiffness gradings of toothbrushes. Tests run at 37 C were 28% less abrasive than those at room temperature, suggesting a softening of bristles because of the warmer temperature. A highly significant abrasive X concentration interaction showed that dentifrices became more than twice as abrasive on dilution form 100 to 50%, but that abrasives alone did not show such changes on dilution. The second study included two hardnesses, two abrasives, three diluents, four concentrations, and two replicates. An interaction was found between abrasive and diluent, showing that glycerine inhibited abrasion by 88% in comparison with saliva and CMC. A hardness X concentration interaction showed that wear varied widely with concentration for the hard brush but scarcely at all for the soft brush. These findings suggest that abrasiveness of dentifrices depends strongly on testing conditions and that no single set of conditions is suitable for evaluating dentifrice abrasiveness.
针对人类牙本质磨损开展了一项五因素研究,该研究涉及两种磨料(单独使用或以牙膏形式使用)、两个牙刷品牌、两种刷毛硬度、两种浓度以及两种测试温度。硬毛牙刷造成的磨损是软毛牙刷的3.6倍,与磨料相比影响更大。牙刷硬度的交互作用表明,牙刷的硬度分级存在很大差异。在37摄氏度下进行的测试比在室温下进行的测试磨损少28%,这表明由于温度较高,刷毛会变软。磨料与浓度之间存在高度显著的交互作用,这表明牙膏在从100%稀释至50%时磨损性增加了两倍多,但单独的磨料在稀释时并未表现出这种变化。第二项研究包括两种硬度、两种磨料、三种稀释剂、四种浓度以及两次重复实验。发现磨料与稀释剂之间存在交互作用,这表明与唾液和羧甲基纤维素相比,甘油可使磨损降低88%。硬度与浓度的交互作用表明,硬毛牙刷的磨损随浓度变化很大,而软毛牙刷几乎没有变化。这些发现表明,牙膏的磨损性在很大程度上取决于测试条件,而且没有一套单一的条件适合评估牙膏的磨损性。