硫唑嘌呤治疗两匹马的免疫介导性血小板减少症。
Azathioprine for treatment of immune-mediated thrombocytopenia in two horses.
作者信息
Humber K A, Beech J, Cudd T A, Palmer J E, Gardner S Y, Sommer M M
机构信息
Department of Clinical Studies, George D. Widener Hospital, New Balton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
出版信息
J Am Vet Med Assoc. 1991 Sep 1;199(5):591-4.
Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone. Platelet counts were increased to acceptable values in both horses. One horse returned to a successful racing career, and the other was euthanatized after developing renal disease and mild laminitis.
硫唑嘌呤是一种硫嘌呤抗代谢物，用于治疗人和犬的免疫性血小板减少症，在2例单独使用皮质类固醇治疗无效的马免疫性血小板减少症中使用。两匹马的血小板计数均升至可接受值。一匹马恢复了成功的赛马生涯，另一匹在患肾病和轻度蹄叶炎后实施了安乐死。
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