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根治性治疗后肺癌患者的随访与监测:ACCP循证临床实践指南(第2版)

Follow-up and surveillance of the lung cancer patient following curative intent therapy: ACCP evidence-based clinical practice guideline (2nd edition).

作者信息

Rubins Jeffrey, Unger Michael, Colice Gene L

机构信息

Pulmonary 111N, One Veterans Dr, Minneapolis, MN 55417, USA.

出版信息

Chest. 2007 Sep;132(3 Suppl):355S-367S. doi: 10.1378/chest.07-1390.

Abstract

BACKGROUND

To develop an evidence-based approach to follow-up of patients after curative intent therapy for lung cancer.

METHODS

Guidelines on lung cancer diagnosis and management published between 2002 and December 2005 were identified by a systematic review of the literature, and supplemental material appropriate to this topic was obtained by literature search of a computerized database (Medline) and review of the reference lists of relevant articles.

RESULTS

Adequate follow-up by the specialist responsible for the curative intent therapy should be ensured to manage complications related to the curative intent therapy and should last at least 3 to 6 months. In addition, a surveillance program should be considered to detect recurrences of the primary lung cancer and/or development of a new primary lung cancer early enough to allow potentially curative retreatment. A standard surveillance program for these patients, coordinated by a multidisciplinary tumor board and overseen by the physician who diagnosed and initiated therapy for the original lung cancer, is recommended based on periodic visits with chest imaging studies and counseling patients on symptom recognition. Smoking cessation and, if indicated, facilitation in participation in special programs is recommended for all patients following curative intent therapy for lung cancer.

CONCLUSIONS

The current evidence favors follow-up of complications related to curative intent therapy, and a surveillance program at regular intervals with imaging and review of symptoms. Smoking cessation after curative intent therapy to prevent recurrence of lung cancer is strongly supported by the available evidence.

摘要

背景

制定一种基于证据的肺癌根治性治疗后患者随访方法。

方法

通过对文献进行系统回顾,确定2002年至2005年12月期间发表的肺癌诊断和管理指南,并通过对计算机数据库(Medline)进行文献检索以及查阅相关文章的参考文献列表,获取适用于该主题的补充材料。

结果

应由负责根治性治疗的专科医生确保进行充分随访,以处理与根治性治疗相关的并发症,随访时间应至少持续3至6个月。此外,应考虑制定一个监测计划,以便尽早发现原发性肺癌的复发和/或新原发性肺癌的发生,从而有可能进行根治性再治疗。建议为这些患者制定一个标准监测计划,该计划由多学科肿瘤委员会协调,并由最初诊断并启动肺癌治疗的医生监督,包括定期进行胸部影像学检查以及就症状识别对患者进行咨询。建议所有接受肺癌根治性治疗的患者戒烟,如有必要,协助其参加特殊项目。

结论

目前的证据支持对与根治性治疗相关的并发症进行随访,并定期进行影像学检查和症状复查的监测计划。现有证据强烈支持根治性治疗后戒烟以预防肺癌复发。

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