Kalkişim Celal, Ozkul M Doğan, Cukurova Ibrahim, Arslan Ilker Burak
Department of Otolaryngology, Tepecik Training and Research Hospital, Izmir, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2007;17(3):143-7.
We investigated arterial blood gas abnormalities in patients presenting with dizziness.
The study included 58 patients (39 females, 19 males; mean age 46 years; range 22 to 74 years) who presented during attacks of dizziness. The duration of vertigo complaints ranged from one day to 30 years. Arterial gas measurements were performed at presentation and one month after treatment. The patients were examined in five groups according to the diagnoses: Meniere's disease (n=14), benign paroxysmal positional vertigo (n=13), vertebrobasilar insufficiency (n=12), vestibular neuritis (n=4), and craniocervical myofascial syndromes (n=15).
At presentation, pH was low (acidosis) in two patients (3.5%), and high (alkalosis) in 15 patients (25.9%). After treatment, all abnormal pH values returned to normal. Twenty-four patients had high or low HCO3- values. High HCO3- values persisted in three patients together with dizziness. Patients with vestibular neuritis had significantly higher PO2 values compared to those with craniocervical myofascial syndrome and vertebrobasilar insufficiency (p<0.05). However, one month after treatment, there were no significant differences between five groups with respect to PO2 levels (p>0.05). Consecutive blood gas measurements did not differ significantly within each diagnosis group (p>0.05).
Our results suggest that arterial blood gas abnormalities may be related to vertigo attacks.
我们研究了以头晕为表现的患者的动脉血气异常情况。
本研究纳入了58例在头晕发作时前来就诊的患者(39例女性,19例男性;平均年龄46岁;范围22至74岁)。眩晕主诉的持续时间从1天到30年不等。在就诊时及治疗1个月后进行动脉血气测量。根据诊断将患者分为五组:梅尼埃病(n = 14)、良性阵发性位置性眩晕(n = 13)、椎基底动脉供血不足(n = 12)、前庭神经炎(n = 4)和颅颈肌筋膜综合征(n = 15)。
就诊时,2例患者(3.5%)pH值低(酸中毒),15例患者(25.9%)pH值高(碱中毒)。治疗后,所有异常的pH值均恢复正常。24例患者的HCO3 - 值高或低。3例患者的高HCO3 - 值与头晕一起持续存在。与颅颈肌筋膜综合征和椎基底动脉供血不足的患者相比,前庭神经炎患者的PO2值显著更高(p < 0.05)。然而,治疗1个月后,五组之间的PO2水平无显著差异(p > 0.05)。每个诊断组内连续的血气测量结果无显著差异(p > 0.05)。
我们的结果表明动脉血气异常可能与眩晕发作有关。