Sethi D S, Stanley R E
Department of Otolaryngology, Singapore General Hospital.
J Laryngol Otol. 1991 Dec;105(12):1025-30. doi: 10.1017/s0022215100118122.
Fifty-five patients with deep neck infections treated consecutively over a period of six and a half years between January 1983 and July 1989 were reviewed. Nine of these patients had abscesses localized to the pharapharyngeal space and form the basis of this study. The aetiology of the parapharyngeal abscess was odontogenic in two patients and remained unknown in the other seven. Five patients had associated systemic disease; four were diabetics and one patient had non-Hodgkin's Lymphoma. High dosage intravenous antibiotics directed towards the causative micro-organisms, airway control and early surgical intervention was the mainstay of treatment. All patients underwent open surgical drainage of the parapharyngeal abscess within 24 h of admission. Bacteriology results showed Klebsiella sp. to be the dominant micro-organism cultured in four patients. Morbidity was low; seven patients had no post-operative complications and were discharged from the hospital between 7-24 d (mean 12.9 d). There were two deaths. Early open surgical drainage remains the most appropriate method of treating parapharyngeal space infections; it avoids life threatening complications with rapid recovery.
回顾了1983年1月至1989年7月期间连续接受治疗的55例颈部深部感染患者。其中9例患者的脓肿局限于咽旁间隙，本研究以此为基础。2例患者咽旁脓肿的病因是牙源性的，其他7例病因不明。5例患者伴有全身性疾病；4例为糖尿病患者，1例为非霍奇金淋巴瘤患者。针对致病微生物的高剂量静脉抗生素治疗、气道控制和早期手术干预是主要治疗方法。所有患者在入院后24小时内均接受了咽旁脓肿的开放手术引流。细菌学结果显示，4例患者培养出的主要微生物为克雷伯菌属。发病率较低；7例患者无术后并发症，于7 - 24天（平均12.9天）出院。有2例死亡。早期开放手术引流仍然是治疗咽旁间隙感染的最合适方法；它可避免危及生命的并发症并实现快速康复。
