Hodges Marcus G, Keane-Myers Andrea M
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland 20852, USA.
Curr Opin Allergy Clin Immunol. 2007 Oct;7(5):424-8. doi: 10.1097/ACI.0b013e3282ef6937.
The purpose of this article is to summarize the clinical presentations associated with the classification of ocular allergy. This article also serves to summarize recent findings of pathophysiological mechanisms associated with ocular allergy and to highlight recently improved diagnostic methods for ocular allergic inflammation.
The term allergic conjunctivitis may not sufficiently describe all forms of allergic eye disease, thus a new classification system is desirable, preferably derived from the varied pathophysiological mechanisms operating in the different forms of ocular allergy. Recent published material has further characterized the roles that inflammatory and structural cells have in ocular allergic inflammation. Improved diagnostic methods have also been developed to assess the underlying causes of ocular allergy.
The underlying immune responses of ocular allergies are complex, indicating the critical need to understand the pathophysiology behind these diseases. Extensive research over the past several years has provided valuable insight into understanding the pathophysiology associated with the different forms of allergic conjunctivitis. Further clarification of the mechanisms associated with different forms of ocular allergy is essential for improved methods of classification, diagnosis, and treatment.
本文旨在总结与眼部过敏分类相关的临床表现。本文还将总结眼部过敏相关病理生理机制的最新研究结果，并重点介绍眼部过敏性炎症最近改进的诊断方法。
“过敏性结膜炎”这一术语可能不足以描述所有形式的过敏性眼病，因此需要一个新的分类系统，最好是基于不同形式眼部过敏中起作用的多种病理生理机制。最近发表的材料进一步明确了炎症细胞和结构细胞在眼部过敏性炎症中的作用。还开发了改进的诊断方法来评估眼部过敏的潜在原因。
眼部过敏的潜在免疫反应很复杂，这表明迫切需要了解这些疾病背后的病理生理学。过去几年的广泛研究为理解与不同形式过敏性结膜炎相关的病理生理学提供了有价值的见解。进一步阐明与不同形式眼部过敏相关的机制对于改进分类、诊断和治疗方法至关重要。
