Lagunju I A, Oluleye T S
Department of Paediatrics, University College Hospital, University of Ibadan, Nigeria.
Afr J Med Med Sci. 2007 Mar;36(1):71-5.
This prospective study was undertaken to evaluate the prevalence of ocular abnormalities, as well as describe the various eye defects seen among cases of cerebral palsy presenting at the Paediatric Neurology Clinic, University College Hospital, Ibadan, Nigeria. All cases of cerebral palsy seen at the Paediatric Neurology Clinic, University College Hospital, Ibadan, over a period of 18 months were carefully evaluated by the Paediatric Neurologist for signs of ocular abnormalities. Those in whom such abnormalities were found were referred to the Consultant Ophthalmologist for detailed eye examination and accurate description of the ocular abnormalities. One hundred and forty nine children with cerebral palsy were seen during the period of study, forty two had associated ocular abnormalities, giving a prevalence rate of 28.2%. More than half (61.9%) of the cases were completely blind. The major ocular abnormalities identified in the affected cases were strabismus (50%), optic atrophy (50%) and cortical visual impairment (47.7%). Other eye defects less frequently seen were nystagmus (9.5%) and refractive errors (4.8%). Presence of spastic quadriplegia was associated with an increased risk of ocular abnormalities. Ocular abnormalities are a frequent problem in children with cerebral palsy. Evaluation of all children with cerebral palsy must include amongst other things, a full ophthalmologic evaluation, even when no gross eye anomalies are visible to the attending physician. Early identification of these defects in children with CP is crucial in order to institute prompt therapy in cases with defects that are amenable to treatment.
本前瞻性研究旨在评估眼部异常的患病率,并描述在尼日利亚伊巴丹大学学院医院儿科神经科门诊就诊的脑瘫患儿中观察到的各种眼部缺陷。在18个月的时间里,伊巴丹大学学院医院儿科神经科门诊的所有脑瘫患儿均由儿科神经科医生仔细评估眼部异常体征。发现有此类异常的患儿被转诊至眼科顾问医生处进行详细的眼部检查,并准确描述眼部异常情况。在研究期间共诊治了149例脑瘫患儿,其中42例伴有眼部异常,患病率为28.2%。超过一半(61.9%)的患儿完全失明。在受影响的病例中确定的主要眼部异常为斜视(50%)、视神经萎缩(50%)和皮质视觉障碍(47.7%)。其他较少见的眼部缺陷为眼球震颤(9.5%)和屈光不正(4.8%)。痉挛性四肢瘫的存在与眼部异常风险增加相关。眼部异常是脑瘫患儿常见的问题。对所有脑瘫患儿的评估必须包括全面的眼科评估等内容,即使主治医生未发现明显的眼部异常。对于脑瘫患儿,早期识别这些缺陷对于那些可治疗的缺陷病例及时开展治疗至关重要。