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北印度儿童的脑瘫:临床病因学特征及合并症

Cerebral Palsy in North Indian Children: Clinico-etiological Profile and Comorbidities.

作者信息

Bhati Parul, Sharma Suvasini, Jain Ridhimaa, Rath B, Beri Sarita, Gupta Vinod K, Aneja Satinder

机构信息

Department of Pediatrics, Lady Hardinge Medical College and Kalawati Saran Children's Hospital, New Delhi, India.

Department of Ophthalmology, Lady Hardinge Medical College and SSK Hospital, New Delhi, India.

出版信息

J Pediatr Neurosci. 2019 Jan-Mar;14(1):30-35. doi: 10.4103/jpn.JPN_46_18.

Abstract

AIMS AND OBJECTIVES

Cerebral palsy (CP) is a common motor disability in children. This study aimed at elaborating various comorbidities and etiologies and also at correlating motor disability with other disabilities.

MATERIAL AND METHODS

This hospital-based study was conducted in the outpatient department of a tertiary care hospital in Delhi on 160 children with CP in the age group 2-15 years. A detailed history taking and examination were conducted for each patient and appropriate investigations were performed.

RESULTS

Most patients, that is 64.4%, were younger than 5 years of age and 72.5% were males. Most common etiology was birth asphyxia (41.9%). Maximum patients were of bilateral spastic (spastic quadriplegic) CP accounting 43.1%. Intellectual disability was the most common comorbidity across all subtypes of CP followed by epilepsy. Comorbidities such as epilepsy and all visual problems except optic atrophy were more common in spastic quadriplegic CP. Hearing, speech impairment, and optic atrophy were more common in dyskinetic CP. Chewing, swallowing, and drooling problems were more common in spastic quadriplegic CP.

CONCLUSION

Most common risk factor of CP is birth asphyxia; thus, by improving health care facilities, its incidence can be reduced. CP affects not only motor functions but also other important functions of body as well, and the more severe the motor disabilities, the more are other comorbidities and their intensity also increases with that of the intensity of brain insult.

摘要

目的与目标

脑性瘫痪(CP)是儿童常见的运动障碍。本研究旨在阐述各种合并症和病因,并将运动障碍与其他残疾进行关联。

材料与方法

本基于医院的研究在德里一家三级护理医院的门诊部对160名年龄在2至15岁的CP患儿进行。对每位患者进行了详细的病史采集和检查,并进行了适当的调查。

结果

大多数患者(64.4%)年龄小于5岁,72.5%为男性。最常见的病因是出生时窒息(41.9%)。最大比例的患者为双侧痉挛性(痉挛性四肢瘫)CP,占43.1%。智力残疾是CP所有亚型中最常见的合并症,其次是癫痫。癫痫以及除视神经萎缩外的所有视力问题等合并症在痉挛性四肢瘫CP中更为常见。听力、言语障碍和视神经萎缩在运动障碍型CP中更为常见。咀嚼、吞咽和流口水问题在痉挛性四肢瘫CP中更为常见。

结论

CP最常见的危险因素是出生时窒息;因此,通过改善医疗保健设施,可以降低其发病率。CP不仅影响运动功能,还影响身体的其他重要功能,运动障碍越严重,其他合并症就越多,且其严重程度也随着脑损伤的严重程度而增加。

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