Muranaka Takashi, Kunishima Yasuharu, Shigyo Masanori, Kato Ryuichi, Masumori Naoya, Ito Naoki, Tsukamoto Taiji, Takagi Yoshio, Seki Masaaki, Toida Ichiro
Department of Urology, Sapporo Medical University.
Hinyokika Kiyo. 2007 Aug;53(8):581-4.
A 51-year-old man received 2 courses of intravesical bacillus Calmette-Guerin (BCG) therapy for carcinoma in situ of the bladder. Two years after the therapy, he underwent left radical nephroureterectomy, cystectomy, urethrectomy and construction of an ileal conduit because of left renal pelvic cancer and severe atrophic bladder. The histopathological diagnosis was carcinoma in situ of the left pelvis and ureter, and epithelioid cell granuloma of left kidney, prostate and bladder. After the operation, he developed extensive surgical site infection (SSI) by BCG, the diagnosis of which was delayed. He recovered from the SSI soon after anti-tuberculosis chemotherapy was begun. We discuss the requirements for more prompt diagnosis of SSI by BCG by analysis of this case.
一名51岁男性因膀胱原位癌接受了2个疗程的膀胱内卡介苗(BCG)治疗。治疗两年后,由于左肾盂癌和严重萎缩性膀胱,他接受了左根治性肾输尿管切除术、膀胱切除术、尿道切除术及回肠代膀胱术。组织病理学诊断为左肾盂和输尿管原位癌,以及左肾、前列腺和膀胱的上皮样细胞肉芽肿。术后,他发生了由BCG引起的广泛手术部位感染(SSI),且诊断延迟。抗结核化疗开始后不久,他从SSI中康复。我们通过分析该病例讨论了更快速诊断BCG引起的SSI的要求。