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足部背侧肿瘤性钙化症的放射学和组织学特征

Radiological and histological features of tumoral calcinosis of the dorsum of the foot.

作者信息

Kotajima S, Hatori M, Ogura K

机构信息

Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan.

出版信息

Australas Radiol. 2007 Oct;51 Spec No.:B85-7. doi: 10.1111/j.1440-1673.2007.01785.x.

DOI:10.1111/j.1440-1673.2007.01785.x
PMID:17875169
Abstract

Tumoral calcinosis is a rare condition characterized by large calcific masses occurring predominantly in the juxta-articular regions of the extremities. To our knowledge, occurrences in the foot, particularly in association with bone erosion, have been very rare. A 52-year-old Japanese man presented with a mass in the foot, the size of which increased over a period of 27 years. CT scan and MRI demonstrated a 6 cm x 3 cm x 2.5 cm sized mass. There was bone erosion of the dorsal side of the third metatarsal head. Marginal excision was made. Histopathologically, the mass was composed of amorphous calcification with inflammatory cell infiltration. X-ray diffraction method revealed that the pattern of the mass coincided with hydroxyapatite. The patients had no local recurrence at 5 years after operation.

摘要

肿瘤性钙化是一种罕见病症,其特征为主要发生在四肢关节周围区域的巨大钙化肿块。据我们所知,足部出现肿瘤性钙化,尤其是伴有骨质侵蚀的情况非常罕见。一名52岁的日本男性患者足部出现肿块,其大小在27年的时间里不断增大。CT扫描和MRI显示有一个大小为6 cm×3 cm×2.5 cm的肿块。第三跖骨头背侧存在骨质侵蚀。进行了边缘切除。组织病理学检查显示,肿块由无定形钙化和炎症细胞浸润组成。X射线衍射法显示肿块的图谱与羟基磷灰石相符。该患者术后5年无局部复发。

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