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Zolpidem abuse, dependence and withdrawal syndrome: sex as susceptibility factor for adverse effects.

作者信息

Cubała Wiesław J, Landowski Jerzy, Wichowicz Hubert M

出版信息

Br J Clin Pharmacol. 2008 Mar;65(3):444-5. doi: 10.1111/j.1365-2125.2007.03028.x. Epub 2007 Sep 13.

DOI:10.1111/j.1365-2125.2007.03028.x
PMID:17875189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2291248/
Abstract
摘要

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Zolpidem abuse, dependence and withdrawal syndrome: sex as susceptibility factor for adverse effects.唑吡坦滥用、依赖及戒断综合征：性别作为不良反应的易感性因素
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2
Zolpidem at supratherapeutic doses can cause drug abuse, dependence and withdrawal seizure.超治疗剂量的唑吡坦可导致药物滥用、依赖和戒断性癫痫发作。
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本文引用的文献

1
Dependence on zolpidem.对唑吡坦的依赖。
Psychiatry Clin Neurosci. 2007 Apr;61(2):207-8. doi: 10.1111/j.1440-1819.2007.01644.x.
2
Seizure following sudden zolpidem withdrawal.突然停用唑吡坦后出现癫痫发作。
Prog Neuropsychopharmacol Biol Psychiatry. 2007 Mar 30;31(2):539-40. doi: 10.1016/j.pnpbp.2006.07.009. Epub 2006 Sep 6.
3
Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.非苯二氮䓬类催眠药唑吡坦和佐匹克隆的滥用及依赖潜力：病例报告与流行病学数据综述
Addiction. 2003 Oct;98(10):1371-8. doi: 10.1046/j.1360-0443.2003.00491.x.
4
Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.唑吡坦在老年人和年轻人中的药代动力学特性：男性体内睾酮可能的调节作用。
Br J Clin Pharmacol. 2003 Sep;56(3):297-304. doi: 10.1046/j.0306-5251.2003.01852.x.
5
Zolpidem-related epileptic seizures: a case report.唑吡坦相关的癫痫发作：一例报告
Eur Psychiatry. 2003 May;18(3):140-1. doi: 10.1016/s0924-9338(03)00031-2.
6
Zolpidem pharmacokinetic properties in young females: influence of smoking and oral contraceptive use.唑吡坦在年轻女性中的药代动力学特性：吸烟和使用口服避孕药的影响。
J Clin Pharmacol. 2002 Oct;42(10):1142-6. doi: 10.1177/009127002401382623.
7
Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences.苯二氮䓬类激动剂三唑仑和唑吡坦的比较动力学及反应：性别依赖性差异评估
J Pharmacol Exp Ther. 2000 May;293(2):435-43.
8
Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations.唑吡坦的体外代谢：相关细胞色素、化学抑制剂及体内相关性
Br J Clin Pharmacol. 1999 Jul;48(1):89-97. doi: 10.1046/j.1365-2125.1999.00953.x.
9
Plasma protein binding of zolpidem in liver and renal insufficiency.
Int J Clin Pharmacol Ther Toxicol. 1988 Sep;26(9):439-43.