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发育中的恒河猴血清胰岛素样生长因子1浓度

Serum insulin-like growth factor 1 concentrations in the developing rhesus monkey.

作者信息

Styne D M

机构信息

Department of Pediatrics, University of California, School of Medicine, Davis 95616.

出版信息

J Med Primatol. 1991 Sep;20(7):334-7.

PMID:1787527
Abstract

We studied the developmental pattern of serum IGF-1 concentrations in the rhesus monkey in cross-sectional and longitudinal manners. Values were lower in infants with a significant rise at the onset of puberty. Females values were lower than males except for pregnant females. There was a correlation of IGF-1 values with body weight in the males. Longitudinal study of six animals proved this age dependence of IGF-1 values. The rhesus monkey has a pattern of serum IGF-1 concentrations similar to that of the human being.

摘要

我们采用横断面和纵向研究方法,对恒河猴血清胰岛素样生长因子-1(IGF-1)浓度的发育模式进行了研究。婴儿期IGF-1值较低,青春期开始时显著升高。除怀孕雌性外,雌性的IGF-1值低于雄性。雄性的IGF-1值与体重相关。对六只动物的纵向研究证实了IGF-1值的这种年龄依赖性。恒河猴血清IGF-1浓度模式与人类相似。

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