Styne D M
Department of Pediatrics, University of California, School of Medicine, Davis 95616.
J Med Primatol. 1991 Sep;20(7):338-44.
We studied the development of the GH response to growth hormone releasing hormone (GHRH) using two doses of GHRH. The newborns demonstrated higher baseline GH and responses to GHRH than animals of any older age. There was no difference noted between the rise in GH in male and female subjects with 10 mcg/kg vs 1 mcg/kg. Serum cortisol concentrations did not correlate with serum GH concentrations. These developmental patterns of serum GH are similar to those known in the human being.
我们使用两种剂量的生长激素释放激素（GHRH）研究了生长激素（GH）对GHRH反应的发育情况。新生儿的基础GH水平和对GHRH的反应高于任何年龄较大的动物。10 mcg/kg与1 mcg/kg剂量下，男性和女性受试者GH升高情况无差异。血清皮质醇浓度与血清GH浓度无相关性。血清GH的这些发育模式与人类已知的模式相似。
