Abdel-Rahman Ulf, Simon Andreas, Ahrens Peter, Heller Klaus, Moritz Anton, Fieguth Hans-Gerd
Department of Thoracic and Cardiovascular Surgery, Theodor-Stern-Kai 7, Johann Wolfgang Goethe-University, D-60590 Frankfurt/Main, Germany.
World J Surg. 2007 Nov;31(11):2255-9. doi: 10.1007/s00268-007-9221-1.
Aortopexy has become an established surgical procedure for the treatment of tracheomalacia (TM) in infants and children. The aim of the present study was to evaluate the clinical outcome and respiratory function after aortopexy in the long term.
Between 1992 and 2006, 20 patients (6 female, 14 male) with TM were treated by bronchoscopically monitored pexis of the aorta via a right anterior thoracotomy. Patient age ranged from 4 months to 11 years (mean: 29 months). Five infants had previous surgery of esophageal atresia or tracheo-esophageal fistulae, and five other patients were operated on for gastroesophageal reflux. Postoperative tidal expiratory flow (TEF25%) was compared to age-related values.
Mean follow-up was 7.8 years (range: 13 months to 10.7 years). There was no early or late mortality. Most patients (n = 16) showed immediate and permanent relief of symptoms. Compared to corresponding age groups, median TEF25% was slightly but not significantly decreased after aortopexy (p = 0.15). In one patient a re-aortopexy was necessary. Another patient experienced recurrent tracheo-esophageal fistula 3 years after aortopexy.
The bronchoscopically guided aortopexy is an efficient and simple method in the surgical treatment of TM in infants and children. The follow-up data in this series of 20 patients showed improvement of respiratory function and permanent relief of symptoms in the long term.
主动脉固定术已成为治疗婴幼儿气管软化症(TM)的既定外科手术。本研究的目的是长期评估主动脉固定术后的临床结果和呼吸功能。
1992年至2006年间,20例TM患者(6例女性,14例男性)通过右前开胸经支气管镜监测进行主动脉固定术。患者年龄从4个月至11岁不等(平均:29个月)。5例婴儿曾接受过食管闭锁或气管食管瘘手术,另外5例患者因胃食管反流接受手术。将术后潮气呼气流量(TEF25%)与年龄相关值进行比较。
平均随访7.8年(范围:13个月至10.7年)。无早期或晚期死亡病例。大多数患者(n = 16)症状立即得到永久性缓解。与相应年龄组相比,主动脉固定术后TEF25%中位数略有下降,但无统计学意义(p = 0.15)。1例患者需要再次进行主动脉固定术。另1例患者在主动脉固定术后3年出现复发性气管食管瘘。
支气管镜引导下的主动脉固定术是治疗婴幼儿TM的一种有效且简单的方法。这组20例患者的随访数据显示,长期来看呼吸功能得到改善,症状得到永久性缓解。