Bezverkhaia T P
Klin Med (Mosk). 1991 Dec;69(12):16-21.
It is the review of literature data on various phenotypic anomalies consequent to the absent or reduced ability of the target tissues to response to androgens (A) due to defects in receptor A structure and function. Clinical forms of resistance to A, quantitative and qualitative abnormalities in hormone-receptor interaction detectable in relevant patients are described as well as markers of target tissue sensitivity to A action suggested for use in prognosticating the response to A treatment.
本文综述了因雄激素（A）受体结构和功能缺陷导致靶组织对雄激素反应能力缺失或降低而引发的各种表型异常的文献资料。文中描述了A抵抗的临床形式、相关患者中可检测到的激素-受体相互作用的定量和定性异常，以及建议用于预测A治疗反应的靶组织对A作用敏感性的标志物。
