Kilbourne Amy M, Brar Jaspreet S, Drayer Rebecca A, Xu Xiangyan, Post Edward P
VA Ann Arbor National Serious Mental Illness Treatment, Research, and Evaluation Center and the Department of Medicine, University of Michigan, Ann Arbor, MI 48105, USA.
Psychosomatics. 2007 Sep-Oct;48(5):412-7. doi: 10.1176/appi.psy.48.5.412.
The authors determined whether diagnoses of cardiovascular disease (CVD) and CVD-related conditions differed by psychiatric diagnosis among male Veterans Administration patients from the mid-Atlantic region. Among 7,529 patients (mean age: 54.5 years), the prevalence of diagnoses ranged from 3.6% (stroke) to 35.4% (hypertension). Compared with schizophrenia patients, those with bipolar disorder were 19% more likely to have diabetes, 44% more likely to have coronary artery disease, and 18% more likely to have dyslipidemia, after adjustment. Clinical suspicion for CVD-related conditions, as well as risk-modification strategies, in patients with serious mental illness should incorporate differences in prevalence across specific psychiatric diagnoses.
作者们确定了来自大西洋中部地区的男性退伍军人管理局患者中，心血管疾病（CVD）及CVD相关病症的诊断在不同精神疾病诊断之间是否存在差异。在7529名患者（平均年龄：54.5岁）中，各诊断的患病率从3.6%（中风）到35.4%（高血压）不等。调整后，与精神分裂症患者相比，双相情感障碍患者患糖尿病的可能性高19%，患冠状动脉疾病的可能性高44%，患血脂异常的可能性高18%。对于患有严重精神疾病的患者，临床对CVD相关病症的怀疑以及风险修正策略应纳入特定精神疾病诊断在患病率方面的差异。
