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一名老年日本2型糖尿病女性双侧乳房的糖尿病性乳腺病:病例报告及日本文献综述

Diabetic mastopathy of bilateral breasts in an elderly Japanese woman with type 2 diabetes: a case report and a review of the literature in Japan.

作者信息

Honda Munehiro, Mori Yasumichi, Nishi Tsunehiro, Mizuguchi Kunio, Ishibashi Miyuki

机构信息

Department of Medicine, Teikyo University School of Medicine, Kawasaki.

出版信息

Intern Med. 2007;46(18):1573-6. doi: 10.2169/internalmedicine.46.6191. Epub 2007 Sep 14.

Abstract

We report a case of diabetic mastopathy in an elderly woman with type 2 diabetes. The patient was a 69-year-old woman diagnosed with type 2 diabetes at the age of 33 years. She had been treated with insulin for 25 years, however, her blood glucose had been poorly controlled. She noticed bilateral breast lumps in September 2002. Mammography of the breast showed increased density in the glandular pattern and architectural distortion without focal mass and microcalcification. Ultrasonography of the breast showed an irregular-shaped hypoechoic mass with an acoustic shadow. As malignancy needed to be excluded, core needle biopsy was performed in the left breast and diabetic mastopathy was confirmed pathologically. Diabetic mastopathy is usually a complication of pre-menopausal type 1 diabetes and develops in a unilateral breast. This case developed in bilateral breasts in an elderly type 2 diabetic patient.

摘要

我们报告一例老年2型糖尿病女性患者的糖尿病性乳腺病。患者为69岁女性,33岁时被诊断为2型糖尿病。她接受胰岛素治疗已25年,然而,其血糖控制不佳。2002年9月她发现双侧乳房肿块。乳腺钼靶检查显示腺体形态密度增加且结构紊乱,无局灶性肿块及微钙化。乳腺超声检查显示一个不规则形低回声肿块,伴有声影。由于需要排除恶性肿瘤,遂对左侧乳房进行了粗针穿刺活检,病理证实为糖尿病性乳腺病。糖尿病性乳腺病通常是绝经前1型糖尿病的并发症,且单侧乳房发病。该病例发生在一名老年2型糖尿病患者的双侧乳房。

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