西班牙加泰罗尼亚省略夫雷加特的普拉特痴呆亚型患病率：PRATICON研究
Prevalence of dementia subtypes in El Prat de Llobregat, Catalonia, Spain: the PRATICON study.
作者信息
Gascón-Bayarri J, Reñé R, Del Barrio J L, De Pedro-Cuesta J, Ramón J M, Manubens J M, Sánchez C, Hernández M, Estela J, Juncadella M, Rubio F R
机构信息
Dementia Unit, Department of Neurology, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain.
出版信息
Neuroepidemiology. 2007;28(4):224-34. doi: 10.1159/000108597. Epub 2007 Sep 19.
BACKGROUND
Studies on dementia subtypes show a wide variation in the prevalence of Alzheimer's disease (AD) and vascular dementia (VD) worldwide. However, studies reporting on Lewy body dementia (LBD) and frontotemporal dementia (FTD) are sparse.
AIMS
To describe the prevalence of dementia and subtypes.
METHOD
A 34% sample of 5,150 subjects aged 70 years and over in El Prat de Llobregat (Barcelona) were screened by the Mini-Mental State Examination. When scoring <24, participants were assessed to establish a diagnosis.
RESULTS
There were 165 subjects diagnosed with dementia (prevalence of 9.4%). Subtypes of dementia were: AD 69.1%, VD 12.7%, LBD 9.1%, FTD 3% and secondary dementia 1.8%. Prevalences were: AD 6.5%, VD 1.2%, LBD 0.9% and FTD 0.3%.
CONCLUSIONS
AD and VD were the most common type of dementia. Prevalence of dementia, AD and FTD were similar to those reported, while prevalence of VD and LBD were lower.
背景
关于痴呆亚型的研究表明，全球范围内阿尔茨海默病（AD）和血管性痴呆（VD）的患病率差异很大。然而，关于路易体痴呆（LBD）和额颞叶痴呆（FTD）的研究报告很少。
目的
描述痴呆及其亚型的患病率。
方法
对巴塞罗那略夫雷加特镇5150名70岁及以上的受试者进行34%抽样，采用简易精神状态检查表进行筛查。得分低于24分时，对参与者进行评估以确定诊断。
结果
有165名受试者被诊断为痴呆（患病率为9.4%）。痴呆亚型为：AD占69.1%，VD占12.7%，LBD占9.1%，FTD占3%，继发性痴呆占1.8%。患病率分别为：AD 6.5%，VD 1.2%，LBD 0.9%，FTD 0.3%。
结论
AD和VD是最常见的痴呆类型。痴呆、AD和FTD的患病率与报告的相似，而VD和LBD的患病率较低。
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