von Lueder Thomas, Steine Kjetil, Nerdrum Tone, Steen Torkel, Bay Dag, Humerfelt Sjur, Atar Dan
Department of Cardiology, Aker University Hospital, University of Oslo, 0514, Oslo, Norway.
Heart Vessels. 2007 Sep;22(5):345-8. doi: 10.1007/s00380-007-0979-8. Epub 2007 Sep 20.
This report describes a patient with a perihilar mass and mediastinal lymphadenopathy mimicking advanced lung cancer. The patient, a 45-year old regular smoker, was admitted to hospital for dyspnea and tachyarrhythmia, and during hospitalization he was diagnosed with severe rheumatic mitral valve stenosis (MVS) and aortic regurgitation as well as pulmonary venous hypertension. Surgical valve replacement and removal of an atrial thrombus was delayed considerably by diagnostic work-up for suspected malignancy. After cardiac surgery had been performed, recovery was uneventful. On follow-up 1 year later, echocardiography showed well-functioning prosthetic mitral and aortic valves, and normal findings on chest X-ray. Perihilar masses and mediastinal lymphadenopathy presented in this case constitute infrequent yet established findings in MVS, resulting from pulmonary venous congestion and hypertension, and focal lymphedema.
本报告描述了一名患者,其肺门周围肿块和纵隔淋巴结肿大酷似晚期肺癌。该患者为一名45岁的长期吸烟者,因呼吸困难和快速心律失常入院,住院期间被诊断为严重风湿性二尖瓣狭窄(MVS)、主动脉瓣反流以及肺静脉高压。由于对疑似恶性肿瘤的诊断检查,手术瓣膜置换和心房血栓清除被大幅推迟。心脏手术后,恢复过程顺利。1年后随访时,超声心动图显示人工二尖瓣和主动脉瓣功能良好,胸部X线检查结果正常。本例中出现的肺门周围肿块和纵隔淋巴结肿大在MVS中虽不常见但已得到确认,是由肺静脉淤血和高压以及局灶性淋巴水肿所致。