• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

贲门失弛缓症合并多发黏膜内癌:一例报告

Achalasia complicated by multiple intramucosal carcinomas: report of a case.

作者信息

Kawasaki Naruo, Suzuki Yutaka, Omura Nobuo, Tsuboi Kazuto, Matsumoto Akira, Kashiwagi Hideyuki, Yanaga Katsuhiko

机构信息

Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo 105-8461, Japan.

出版信息

Surg Today. 2007;37(10):897-900. doi: 10.1007/s00595-007-3505-9. Epub 2007 Sep 26.

DOI:10.1007/s00595-007-3505-9
PMID:17879043
Abstract

A 56-year-old woman underwent a laparoscopic Heller-Dor operation for esophageal achalasia in June 2002. As dysphagia became exacerbated and the oral intake became extremely poor, an esophagectomy was thus considered to be indicated. In September 2005, a transhiatal esophagectomy was performed, and the esophagus was reconstructed using a gastric tube through the posterior mediastinum. The patient developed pneumonia postoperatively, but responded to conservative therapy and was discharged in good health 30 days after surgery. A histopathological analysis demonstrated degeneration and a loss of gangliocytes throughout the esophagus as well as the presence of seven intramucosal cancers. The main cause of dysphagia was due to a marked flexion of the upper esophagus. Even though we identified a precancerous state, we believe that surgery was an appropriate option in this case.

摘要

一名56岁女性于2002年6月接受了腹腔镜下Heller-Dor手术治疗食管贲门失弛缓症。由于吞咽困难加重且经口摄入量极差,因此考虑行食管切除术。2005年9月,进行了经胸食管切除术,并通过后纵隔使用胃管重建食管。患者术后发生肺炎,但经保守治疗后好转,术后30天健康出院。组织病理学分析显示整个食管神经节细胞变性和缺失,以及存在7处黏膜内癌。吞咽困难的主要原因是食管上段明显弯曲。尽管我们发现了癌前状态,但我们认为在这种情况下手术是合适的选择。

相似文献

1
Achalasia complicated by multiple intramucosal carcinomas: report of a case.贲门失弛缓症合并多发黏膜内癌:一例报告
Surg Today. 2007;37(10):897-900. doi: 10.1007/s00595-007-3505-9. Epub 2007 Sep 26.
2
Esophageal adenocarcinoma: pseudo-nutcracker esophagus.食管腺癌:假性贲门失弛缓症。
Dysphagia. 2009 Jun;24(2):234-7. doi: 10.1007/s00455-008-9175-y. Epub 2008 Jul 15.
3
Recurrent dysphagia after Heller myotomy: is esophagectomy always the answer?食管肌切开术后反复吞咽困难:是否总是需要行食管切除术?
J Am Coll Surg. 2013 Apr;216(4):736-43; discussion 743-4. doi: 10.1016/j.jamcollsurg.2012.12.008. Epub 2013 Feb 12.
4
Laparoscopic treatment of recurrent dysphagia following transthoracic myotomy for achalasia.腹腔镜治疗贲门失弛缓症经胸肌切开术后复发性吞咽困难。
J Laparoendosc Adv Surg Tech A. 2003 Dec;13(6):401-3. doi: 10.1089/109264203322656487.
5
Laparoscopic approach for esophageal achalasia with epiphrenic diverticulum.腹腔镜治疗合并膈上憩室的食管贲门失弛缓症
Surg Laparosc Endosc Percutan Tech. 2001 Apr;11(2):112-5.
6
Misinsertion of an esophageal bougie between the mucosa and muscular layer of the lower esophagus during operation in a case of achalasia.在一例贲门失弛缓症手术过程中,食管探条误插入食管下段黏膜与肌层之间。
Surg Laparosc Endosc Percutan Tech. 2009 Dec;19(6):e230-2. doi: 10.1097/SLE.0b013e3181bd92bf.
7
Laparoscopic surgery for an unusual case of dysphagia: lower oesophageal leiomyoma co-existing with achalasia cardia.腹腔镜手术治疗一例罕见吞咽困难病例:食管下段平滑肌瘤合并贲门失弛缓症。
Singapore Med J. 2008 Jan;49(1):e22-5.
8
[Dolichomegaesophagus in achalasia. Therapy by esophogectomy in an aged patient].
Dtsch Med Wochenschr. 2004 Apr 2;129(14):735-8. doi: 10.1055/s-2004-821378.
9
Laparoscopic Heller myotomy relieves dysphagia in patients with achalasia and low LES pressure following pneumatic dilatation.腹腔镜下Heller肌切开术可缓解贲门失弛缓症患者在气囊扩张后出现的吞咽困难及较低的食管下括约肌压力。
Surg Endosc. 2001 Jul;15(7):687-90. doi: 10.1007/s004640080098. Epub 2001 May 11.
10
Transthoracic Heller myotomy for esophageal achalasia: analysis of long-term results.经胸Heller肌切开术治疗食管贲门失弛缓症:长期结果分析
Ann Thorac Surg. 2006 Jun;81(6):2044-9. doi: 10.1016/j.athoracsur.2006.01.039.

本文引用的文献

1
Long-term follow-up after pneumatic dilation for achalasia cardia: factors associated with treatment failure and recurrence.贲门失弛缓症气囊扩张术后的长期随访:与治疗失败和复发相关的因素
Am J Gastroenterol. 2004 Dec;99(12):2304-10. doi: 10.1111/j.1572-0241.2004.40099.x.
2
Squamous mucosal alterations in esophagectomy specimens from patients with end-stage achalasia.
Am J Surg Pathol. 2001 Nov;25(11):1413-8. doi: 10.1097/00000478-200111000-00009.
3
Laparoscopic cardiomyotomy and anterior partial fundoplication for achalasia.腹腔镜下贲门肌层切开术及前位部分胃底折叠术治疗贲门失弛缓症
Surg Endosc. 2001 Jul;15(7):683-6. doi: 10.1007/s004640080037. Epub 2001 May 7.
4
Achalasia and esophageal cancer: incidence, prevalence, and prognosis.贲门失弛缓症与食管癌:发病率、患病率及预后
World J Surg. 2001 Jun;25(6):745-9. doi: 10.1007/s00268-001-0026-3.
5
Clinicopathological studies of esophageal carcinoma in achalasia: analyses of carcinogenesis using histological and immunohistochemical procedures.贲门失弛缓症患者食管癌的临床病理研究:运用组织学和免疫组化方法分析致癌机制
Anticancer Res. 2000 Sep-Oct;20(5C):3717-22.
6
Laparoscopic Heller myotomy relieves dysphagia in achalasia when the esophagus is dilated.当食管扩张时,腹腔镜下贲门肌层切开术可缓解贲门失弛缓症的吞咽困难。
Surg Endosc. 1999 Sep;13(9):843-7. doi: 10.1007/s004649901117.
7
Early cancer in achalasia.
Dis Esophagus. 1998 Oct;11(4):239-47. doi: 10.1093/dote/11.4.239.
8
Pathophysiology and endoscopic/balloon treatment of esophageal motility disorders.
Surg Clin North Am. 1997 Oct;77(5):971-92. doi: 10.1016/s0039-6109(05)70601-0.
9
Laparoscopic Heller myotomy and fundoplication for achalasia.腹腔镜下Heller肌切开术及贲门折叠术治疗贲门失弛缓症。
Ann Surg. 1997 Jun;225(6):655-64; discussion 664-5. doi: 10.1097/00000658-199706000-00003.
10
Individual prediction of response to pneumatic dilation in patients with achalasia.贲门失弛缓症患者对气囊扩张反应的个体预测
Dig Dis Sci. 1996 Nov;41(11):2135-41. doi: 10.1007/BF02071392.