胚胎干细胞多能性和自我更新的分子机制。
The molecular mechanism of embryonic stem cell pluripotency and self-renewal.
作者信息
Liu YuXiao, Ji Lei, Ten Yue, Wang YunFang, Pei XueTao
机构信息
Laboratory of Stem Cell Biology, Beijing Institution of Transfusion Medicine, Beijing 100850, China.
出版信息
Sci China C Life Sci. 2007 Oct;50(5):619-23. doi: 10.1007/s11427-007-0074-5.
PMID:17879059
Abstract
The self-renewal and pluripotency of embryonic stem cells (ESCs) is regulated by a network, which consists of a series of cell factors in microenviroments, a chain of transcription factors and certain signal conduction pathways. This article reviews recent progress in this field to elucidate the mechanism involved.
摘要
胚胎干细胞（ESCs）的自我更新和多能性受一个网络调控，该网络由微环境中的一系列细胞因子、一连串转录因子和某些信号传导通路组成。本文综述了该领域的最新进展以阐明其中涉及的机制。
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