Ogawa Atsushi, Hamamoto Kunihiro, Hirose Shinichi, Fujikawa Maiko, Mitsudome Akihisa
Department of Pediatrics, School of Medicine, Fukuoka University, Fukuoka.
No To Hattatsu. 2007 Sep;39(5):347-50.
To elucidate autonomic function in individuals with severe motor and intellectual disabilities, we evaluated sympathetic skin response in 14 patients with severe motor and intellectual disabilities. The results of sympathetic skin response were compared with those of patients with mild or moderate motor and intellectual disabilities who could walk and had an intelligence quotient > or = 35 (7 cases) and neuromuscular diseases (3 cases). No sympathetic skin response was recorded in patients with severe motor and intellectual disabilities, whereas all patients with mild or moderate motor and intellectual disabilities defined above and neuromuscular diseases showed sympathetic skin response. The results suggested that all patients with severe motor and intellectual disabilities had autonomic dysfunction, and sympathetic skin response can be a useful test that can evaluate autonomic function in patients with severe motor and intellectual disabilities.
为阐明重度运动和智力残疾个体的自主神经功能，我们评估了14例重度运动和智力残疾患者的交感神经皮肤反应。将交感神经皮肤反应的结果与能够行走且智商≥35的轻度或中度运动和智力残疾患者（7例）以及神经肌肉疾病患者（3例）的结果进行了比较。重度运动和智力残疾患者未记录到交感神经皮肤反应，而上述所有轻度或中度运动和智力残疾患者以及神经肌肉疾病患者均表现出交感神经皮肤反应。结果表明，所有重度运动和智力残疾患者均存在自主神经功能障碍，交感神经皮肤反应可作为评估重度运动和智力残疾患者自主神经功能的一项有用检测方法。
