Visokai V, Lipská L, Záruba P, Rotnágl J
Chirurgická klinika FTN Praha a 1. LF UK.
Rozhl Chir. 2007 Jul;86(7):370-5.
Intrahepatic lithiasis (IHL) has a low incidence rate in countries with high social-economical level, with mostly secondary ethiology. The commonest signs include: cholangoitis, obstruction icterus, liver absces and secondary biliary cirrhosis. Although a wide range of treatment methods is available, in some cases, surgical management is the only alternative.
The authors present two case reviews of IHL patients. The first case includes a 56-year old male, unsuccessfuly operated in another clinic. The patient was referred to the author's clinic for a relaps of septic complications. He underwent extensive revision of his bile ducts up to the segmental bile duct level with a mechanical removal of concrements, introduction of the T-drain and postoperative cholangiography for secondary IHL of the left hepatic duct. A resection procedure was not indicated due to absence of the liver parenchyma impairment. The other patient, a 77-year old male, underwent left lateral bisegmentectomy for a primary IHL of the SII and SIII liver segments with signs of irreversible bile duct impairment, which could not be managed endoscopically.
No complications during the first patient's postoperative course were recorded. A postoperative Day 7 cholangiographic examination detected free intrahepatic bile ducts. The patient has not shown any signs of a IHL relaps. The second patient's postoperative course was complicated by biliary secretion from the drain, which was managed endoscopically. A histological examination confirmed the preoperative diagnosis.
IHL which cannot be managed by endoscopy or other procedures, is indicated for surgery. The type of the surgical procedure depends on the extent of the intrahepatic bile duct and liver parenchyma impairment.
肝内胆管结石(IHL)在社会经济水平较高的国家发病率较低,多为继发性病因。最常见的症状包括:胆管炎、梗阻性黄疸、肝脓肿和继发性胆汁性肝硬化。尽管有多种治疗方法可供选择,但在某些情况下,手术治疗是唯一的选择。
作者介绍了两例IHL患者的病例回顾。第一例患者为一名56岁男性,在另一家诊所手术失败。该患者因败血症并发症复发被转诊至作者所在诊所。他接受了广泛的胆管修复,直至肝段胆管水平,机械清除结石,置入T形引流管,并进行术后胆管造影,以治疗左肝管继发性IHL。由于肝实质未受损,未行切除手术。另一例患者为一名77岁男性,因SII和SIII肝段原发性IHL伴不可逆胆管损伤迹象,无法通过内镜治疗,接受了左外侧双段切除术。
第一例患者术后过程未记录到并发症。术后第7天的胆管造影检查发现肝内胆管通畅。患者未出现IHL复发迹象。第二例患者术后过程出现引流管胆汁分泌并发症,通过内镜治疗。组织学检查证实了术前诊断。
无法通过内镜或其他方法治疗的IHL,建议手术治疗。手术方式取决于肝内胆管和肝实质损伤的程度。