Pikuza O I, Merfogel' M S, Muslimov I Kh
Pediatriia. 1991(10):13-5.
As many as 63 infants with acute pneumonia, 7 children with ARVI (bronchiolitis) and 28 normal children were examined. At the height of the clinical manifestations there was an increase of the level of medium-weight molecules in blood serum, correlating well with the disease gravity determined by the intensity of the toxic syndrome. The highest concentration of serum medium-weight molecules was demonstrable in toxic and purulent complications due to acute pneumonia. Meanwhile the level of medium-weight molecules, equal to or exceeding 0.6 Units extinction may be viewed as an unfavourable predictor. No relationship was discovered between the concentration of serum medium-weight molecules and the type of virus causative agent and respiratory tract inflammation.
对63例急性肺炎患儿、7例急性呼吸道病毒感染（细支气管炎）患儿和28例正常儿童进行了检查。在临床表现高峰期，血清中中等分子量分子水平升高，这与由中毒综合征强度所确定的疾病严重程度密切相关。血清中等分子量分子的最高浓度在急性肺炎所致的中毒性和化脓性并发症中表现明显。同时，血清中等分子量分子水平等于或超过0.6消光单位可被视为不良预后指标。未发现血清中等分子量分子浓度与病毒病原体类型及呼吸道炎症之间存在关联。
