聚合物负载的2-碘苯酚醚的制备及其反应活性，一种高效可回收的氧化体系。

Preparation and reactivity of polymer-supported 2-iodylphenol ethers, an efficient recyclable oxidizing system.

作者信息

Karimov Rashad R, Kazhkenov Zeinul-Gabiden M, Modjewski Matthew J, Peterson Eric M, Zhdankin Viktor V

机构信息

Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, Minnesota 55812, USA.

出版信息

J Org Chem. 2007 Oct 12;72(21):8149-51. doi: 10.1021/jo7015746. Epub 2007 Sep 20.

DOI:10.1021/jo7015746

PMID:17880245

Abstract

Preparation of new recyclable polymer-supported oxidizing reagents based on 2-iodylphenol ethers is described. The synthesis employs commercially available aminomethylated polystyrene or Merrifield resin and affords polymer-supported 2-iodylphenol ethers with loading up to 0.86 mmol/g with respect to IO2 groups. The new reagents effect clean and efficient conversion of a wide range of alcohols, including heteroatomic and unsaturated structures, to the corresponding carbonyl compounds. Recycling of the resins is possible with minimal loss of activity after several reoxidations.

摘要

描述了基于2-碘苯酚醚制备新型可回收聚合物负载氧化试剂的方法。该合成方法采用市售的氨甲基化聚苯乙烯或Merrifield树脂，得到聚合物负载的2-碘苯酚醚，相对于IO2基团的负载量高达0.86 mmol/g。这些新型试剂能将包括含杂原子和不饱和结构在内的多种醇类干净、高效地转化为相应的羰基化合物。树脂经过几次再氧化后，活性损失最小，可实现回收利用。