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鼻内去氨加压素(奥曲肽):治疗出血性疾病儿童的一种安全有效的选择。

Intranasal desmopressin (Octim): a safe and efficacious treatment option for children with bleeding disorders.

作者信息

Khair K, Baker K, Mathias M, Burgess C, Liesner R

机构信息

Haemophilia Comprehensive Care Centre, Great Ormond Street Hospital for Children NHS Trust, London, UK.

出版信息

Haemophilia. 2007 Sep;13(5):548-51. doi: 10.1111/j.1365-2516.2007.01519.x.

Abstract

Desmopressin (1-deamino-8-D-arginine vasopressin (DDAVP)) has been shown to be an effective treatment option when administered both intravenously [1,2] and subcutaneously [3] to children with inherited bleeding disorders. We demonstrate here, both the efficacy and acceptability of a new intranasal DDAVP preparation, providing a cost effective treatment with good outcomes for children with bleed disorders.

摘要

去氨加压素(1-去氨基-8-D-精氨酸加压素(DDAVP))已被证明,对于患有遗传性出血性疾病的儿童,静脉注射[1,2]和皮下注射[3]时都是一种有效的治疗选择。我们在此证明了一种新的鼻内DDAVP制剂的有效性和可接受性,为出血性疾病儿童提供了一种具有良好效果的经济高效的治疗方法。

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