Al-Maskari Fatma, El-Sadig Mohammed, Norman John N
Department of Community Medicine, Faculty of Medicine & Health Sciences, United Arab Emirates University, Al-Ain, PO Box: 17666, UAE.
Cardiovasc Diabetol. 2007 Sep 19;6:24. doi: 10.1186/1475-2840-6-24.
Diabetes Mellitus (DM) is a major public health problem in the UAE with a prevalence rate reaching 24% in national citizens and 17.4% in expatriates. The aim of this study was to determine the prevalence and risk factors of macrovascular complications among diabetic patients in the Al-Ain district of the United Arab Emirates (UAE).
The study was part of a general cross-sectional survey carried out to assess the prevalence of diabetes (DM) complications among known diabetic patients in Al-Ain District, UAE. Patients were randomly selected during 2003/2004. Patients completed an interviewer-administered questionnaire carried out by treating doctors and underwent a complete medical assessment including measurement of height, weight, blood pressure and examination for evidence of macrovascular complications. A standard ECG was recorded and blood samples were taken to document fasting blood sugar, glycosylated haemoglobin (HbA1C) and lipid profile.
A sample of 513 diabetic patients was selected with a mean age of 53 years (SD +/- 13.01). Overall, 29.5% of DM patients had evidence of macrovascular complications: 11.6% (95% CI: 8.8-14.4) of patients had peripheral vascular disease (PVD), 14.4% (95% CI: 11.3-17.5) had a history of coronary artery disease (CAD) and 3.5% (95% CI: 1.9-5.1%) had cerebrovascular disease (CVD). Of the total population surveyed 35% (95%CI: 30.8-39) had hypertension. The analysis showed that macrovascular complications in diabetic patients were more common among males, increased with age, were more common among hypertensive patients and its prevalence increased steadily with duration of DM.
Our data revealed a significant association between hypertension and presence of macrovascular disease among diabetic patients. However, the risk of CAD in the UAE was relatively low compared to that seen in patients in other geographical settings. In addition, a lack of correlation between macrovascular disease and glycemic control among patients with DM was observed.
糖尿病(DM)是阿联酋的一个主要公共卫生问题,本国公民患病率达24%,外籍人士患病率为17.4%。本研究旨在确定阿拉伯联合酋长国(阿联酋)艾因地区糖尿病患者大血管并发症的患病率及危险因素。
该研究是一项横断面调查的一部分,旨在评估阿联酋艾因地区已知糖尿病患者的糖尿病(DM)并发症患病率。于2003/2004年随机选取患者。患者完成由主治医生进行的访谈式问卷调查,并接受包括身高、体重、血压测量及大血管并发症证据检查在内的全面医学评估。记录标准心电图并采集血样,以记录空腹血糖、糖化血红蛋白(HbA1C)和血脂谱。
选取了513例糖尿病患者样本,平均年龄53岁(标准差±13.01)。总体而言,29.5%的糖尿病患者有大血管并发症证据:11.6%(95%置信区间:8.8 - 14.4)的患者有外周血管疾病(PVD),14.4%(95%置信区间:11.3 - 17.5)有冠状动脉疾病(CAD)病史,3.5%(95%置信区间:1.9 - 5.1%)有脑血管疾病(CVD)。在全部调查人群中,35%(95%置信区间:30.8 - 39)患有高血压。分析表明,糖尿病患者的大血管并发症在男性中更常见,随年龄增加而增多,在高血压患者中更常见,且其患病率随糖尿病病程稳步上升。
我们的数据显示糖尿病患者中高血压与大血管疾病的存在之间存在显著关联。然而,与其他地理区域的患者相比,阿联酋CAD的风险相对较低。此外,观察到糖尿病患者中大血管疾病与血糖控制之间缺乏相关性。