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心脏手术后早期的6分钟步行试验。参考值及康复计划的效果。

The 6-min walking test early after cardiac surgery. Reference values and the effects of rehabilitation programme.

作者信息

Fiorina Claudia, Vizzardi Enrico, Lorusso Roberto, Maggio Marcello, De Cicco Giuseppe, Nodari Savina, Faggiano Pompilio, Dei Cas Livio

机构信息

Cardiology Division, University of Brescia, Brescia, Italy.

出版信息

Eur J Cardiothorac Surg. 2007 Nov;32(5):724-9. doi: 10.1016/j.ejcts.2007.08.013. Epub 2007 Sep 18.

Abstract

BACKGROUND

The 6-min walking test (6MWT) is a simple test, which does not require expensive equipment or advanced training. It has been used in heart failure patients to assess exercise tolerance, the effects of therapy and prognosis. Accordingly, post-surgical cardiac rehabilitation may be a potential field of application of this test.

MATERIALS AND METHOD

One thousand three hundred seventy patients (70% males, mean age 64+/-10 years), consecutively admitted for intensive cardiac rehabilitation, underwent 6MWT within 15 days after different types of cardiac surgery (67% coronary artery bypass graft (CABG), 25% valve replacement, 4% both, 4% other). The 6MWT was repeated in a subgroup of 348 patients after 15+/-3 days of an in-hospital cardiac rehabilitation programme.

RESULTS

6MWT (expressed as absolute value in metres and as a percentage of the predicted value) was well tolerated in all patients. The mean distance walked in 1370 patients was 304+/-89 m (corresponding to 58+/-15% of the predicted value). Distances walked were significantly shorter in older patients than younger (p<0.05) and in women compared to men (251+/-78 m, 53+/-15%, vs 328+/-34 m, 60+/-14%, p<0.001). Furthermore, the absolute distance walked in 6 min was significantly shorter in diabetics compared to non-diabetics (283+/-85 m vs 302+/-87 m, p=0.001) and in no CABG compared to CABG patients (285+/-91 m vs 303+/-84 m, p<0.001); no relation was found between distance walked and left ventricular ejection fraction (p=0.5). Gender, age, comorbidities and type of surgery were independently associated with 6MWT in the multivariate model. In the subgroup of patients repeating the 6MWT after the rehabilitation programme, the distance walked significantly increased (from 281+/-90 m, 51+/-76%, to 411+/-107 m, 77+/-81%, p<0.001). The extent of improvement observed was similar according to sex, age, presence/absence of diabetes and type of surgery.

CONCLUSIONS

Our data suggest that 6MWT is feasible and well tolerated in adult and older patients shortly after uncomplicated cardiac surgery and provides reference values for distance walked after cardiac surgery in this population.

摘要

背景

6分钟步行试验(6MWT)是一项简单的测试,不需要昂贵的设备或高级培训。它已被用于心力衰竭患者,以评估运动耐量、治疗效果和预后。因此,心脏术后康复可能是该测试的一个潜在应用领域。

材料与方法

1370例患者(70%为男性,平均年龄64±10岁)因接受强化心脏康复连续入院,在接受不同类型心脏手术后15天内进行了6MWT(67%为冠状动脉旁路移植术(CABG),25%为瓣膜置换术,4%两者皆有,4%为其他)。348例患者在住院心脏康复计划进行15±3天后重复进行了6MWT。

结果

所有患者对6MWT(以米为单位的绝对值和预测值的百分比表示)耐受性良好。1370例患者的平均步行距离为304±89米(相当于预测值的58±15%)。老年患者步行的距离明显短于年轻患者(p<0.05),女性短于男性(251±78米,53±15%,对比328±34米,60±14%,p<0.001)。此外,糖尿病患者6分钟内步行的绝对距离明显短于非糖尿病患者(283±85米对比302±87米,p=0.001),未进行CABG的患者短于CABG患者(285±91米对比303±84米,p<0.001);步行距离与左心室射血分数之间未发现相关性(p=0.5)。在多变量模型中,性别、年龄、合并症和手术类型与6MWT独立相关。在康复计划后重复进行6MWT的患者亚组中,步行距离显著增加(从281±90米,51±76%,增加到411±107米,77±81%,p<0.001)。根据性别、年龄、是否患有糖尿病和手术类型观察到的改善程度相似。

结论

我们的数据表明,6MWT在简单心脏手术后不久的成年和老年患者中是可行的且耐受性良好,并为该人群心脏手术后的步行距离提供了参考值。

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