Araki Naoya, Hirota Takafumi, Hidaka Hideaki, Horibe Tatsuya, Numaguchi Ryosuke, Takaki Jun, Nishigawa Kosaku, Yoshinaga Takashi, Fukui Toshihiro
Department of Cardiovascular Surgery, Kumamoto University Hospital Kumamoto Japan.
Circ Rep. 2023 Jul 11;5(8):317-322. doi: 10.1253/circrep.CR-23-0060. eCollection 2023 Aug 10.
This single-center retrospective analysis investigated the number of days required for postoperative 6-minute walk distance (6MWD) to recover to preoperative values after coronary artery bypass grafting (CABG) and the factors influencing this recovery. The 6MWD was measured in 101 patients (median age 69 years; 18 women) before and every day after CABG. Univariate and multivariate analyses were performed to identify factors affecting 6MWD recovery to preoperative values after CABG. The median number of days required for recovery of 6MWD after CABG was 9 (interquartile range 7-11 days). Patients were divided into 2 groups based on the median number of days required for recovery of 6MWD; there were 60 patients in the early recovery group (<9 days) and 41 in the "non-early" recovery group (38 who recovered after the median 9 days, and 3 who did not recover during hospitalization). Using univariate logistic regression analysis, diabetes (P=0.01), stroke (P=0.26), left ventricular ejection fraction (P=0.27), and grip strength (P=0.13) were selected for multivariate analysis. Multivariate logistic regression analysis revealed that diabetes (odds ratio 2.955; 95% confidence interval 1.208-7.229; P=0.02) was the only independent predictor of 6MWD recovery. Diabetes was the single factor influencing the recovery of postoperative 6MWD in patients undergoing CABG.
这项单中心回顾性分析调查了冠状动脉旁路移植术(CABG)后术后6分钟步行距离(6MWD)恢复到术前值所需的天数以及影响这种恢复的因素。在101例患者(中位年龄69岁;18名女性)中,于CABG术前及术后每日测量6MWD。进行单因素和多因素分析以确定影响CABG术后6MWD恢复到术前值的因素。CABG术后6MWD恢复所需的中位天数为9天(四分位间距7 - 11天)。根据6MWD恢复所需的中位天数将患者分为两组;早期恢复组(<9天)有60例患者,“非早期”恢复组有41例患者(38例在中位9天后恢复,3例在住院期间未恢复)。使用单因素逻辑回归分析,选择糖尿病(P = 0.01)、中风(P = 0.26)、左心室射血分数(P = 0.27)和握力(P = 0.13)进行多因素分析。多因素逻辑回归分析显示,糖尿病(比值比2.955;95%置信区间1.208 - 7.229;P = 0.02)是6MWD恢复的唯一独立预测因素。糖尿病是影响接受CABG患者术后6MWD恢复的单一因素。