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第三脑神经海绵状血管瘤:病例报告

Cavernous hemangioma of the third cranial nerve: case report.

作者信息

Itshayek Eyal, Perez-Sanchez Xicotencatl, Cohen Jose E, Umansky Felix, Spektor Sergey

机构信息

Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

出版信息

Neurosurgery. 2007 Sep;61(3):E653; discussion E653. doi: 10.1227/01.NEU.0000290916.63094.8E.

Abstract

OBJECTIVE

The authors report a rare case of a cavernous hemangioma (CH) involving the third cranial nerve.

CLINICAL PRESENTATION

A 25-year-old Caucasian woman presented with neuralgic facial pain that responded to pharmacological management. She had no neurological deficit. Magnetic resonance imaging scans revealed a space-occupying lesion in the interpeduncular cistern with no evidence of hemorrhagic event. Preoperative cerebrospinal fluid and blood samples were negative for cytology and tumor markers.

INTERVENTION

The patient underwent craniotomy and exploration of the interpeduncular cistern. A lesion with the raspberry-like appearance characteristic of a CH was found emerging from between the fibers and completely encircling Cranial Nerve III. The surgeon decided to leave the lesion in place to avoid creation of a new neurological deficit in the young patient. The patient is asymptomatic with a stable radiological picture 18 months after surgery.

CONCLUSION

CH should be considered as a possible differential diagnosis of extra-axial space-occupying lesions along the course of the cranial nerves. Resection with resulting deficit may not be indicated in patients presenting with normal neurological function. Further research and longer follow-up periods are required to better understand the natural history of CH involving the cranial nerves.

摘要

目的

作者报告一例罕见的累及第三脑神经的海绵状血管瘤(CH)病例。

临床表现

一名25岁的白种女性出现神经性面部疼痛,经药物治疗有效。她没有神经功能缺损。磁共振成像扫描显示脚间池有占位性病变,无出血事件迹象。术前脑脊液和血液样本的细胞学及肿瘤标志物检查均为阴性。

干预措施

患者接受了开颅手术并探查脚间池。发现一个具有CH典型覆盆子样外观的病变,从纤维之间长出并完全包绕第三脑神经。外科医生决定保留病变,以避免给这位年轻患者造成新的神经功能缺损。术后18个月,患者无症状,影像学表现稳定。

结论

CH应被视为沿脑神经走行的轴外占位性病变的一种可能鉴别诊断。对于神经功能正常的患者,可能不建议进行切除手术以免造成功能缺损。需要进一步研究和更长的随访期,以更好地了解累及脑神经的CH的自然病程。

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