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动眼神经海绵状血管瘤切除术。

Resection of an oculomotor nerve cavernous angioma.

作者信息

Obaid Sami, Li Shu, Denis Daniel, Weil Alexander G, Bojanowski Michel W

机构信息

Division of Neurosurgery, Hôpital Notre-Dame du CHUM, University of Montreal, Montreal, Quebec, Canada.

Division of Neurosurgery, Hôpital Notre-Dame du CHUM, University of Montreal, Montreal, Quebec, Canada ; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

Surg Neurol Int. 2014 Jul 30;5(Suppl 4):S203-7. doi: 10.4103/2152-7806.137754. eCollection 2014.

DOI:10.4103/2152-7806.137754
PMID:25184101
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4138817/
Abstract

BACKGROUND

Cavernous angiomas (CAs) of cranial nerves are rare, and their occurrence on the third cranial nerve is particularly rare. Surgical management of such CAs involving the third nerve is controversial. We describe a case of a symptomatic CA of the oculomotor nerve and review the literature in order to ascertain the relevance of surgical intervention.

CASE DESCRIPTION

A 71-year-old male patient presented with a 2-month history of progressive oculomotor nerve paralysis. CA of the oculomotor nerve was suspected on magnetic resonance imaging (MRI). The patient underwent complete resection of the CA through a subtemporal approach, preserving the integrity of the nerve. Histopathological analysis confirmed the diagnosis of CA. Despite optimal resection, the patient did not improve postoperatively.

CONCLUSION

CAs of cranial nerves can cause rapid or progressive neurological deterioration. Whereas delayed treatment often leads to irreversible deficits, early nerve-sparing surgical excision of the CAs may potentially restore function.

摘要

背景

颅神经海绵状血管瘤(CAs)较为罕见,而发生于第三颅神经的情况尤为罕见。此类累及第三神经的CAs的手术治疗存在争议。我们描述一例动眼神经症状性CAs病例并回顾相关文献,以确定手术干预的相关性。

病例描述

一名71岁男性患者,有2个月进行性动眼神经麻痹病史。磁共振成像(MRI)怀疑为动眼神经CAs。患者通过颞下入路对CAs进行了完整切除,保留了神经的完整性。组织病理学分析证实为CAs诊断。尽管进行了最佳切除,但患者术后并未改善。

结论

颅神经CAs可导致快速或进行性神经功能恶化。虽然延迟治疗常导致不可逆的功能缺损,但早期保留神经的CAs手术切除可能恢复功能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/b2c39601ce29/SNI-5-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/550427e506b0/SNI-5-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/1e6a24d0b889/SNI-5-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/403cfb94b361/SNI-5-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/b2c39601ce29/SNI-5-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/550427e506b0/SNI-5-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/1e6a24d0b889/SNI-5-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/403cfb94b361/SNI-5-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72b7/4138817/b2c39601ce29/SNI-5-203-g004.jpg

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Multiple supra- and infratentorial cavernous hemangiomas in a five year-old girl.一名5岁女孩患有多发幕上和幕下海绵状血管瘤。

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Neurosurgery. 2005 Mar 1;56(3):E623. doi: 10.1227/01.NEU.0000154063.05728.7E.
2
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Neurosurgery. 2011 Aug;69(2):E470-4. doi: 10.1227/NEU.0b013e31821cc21f.
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Cavernous malformation of the cisternal trigeminal nerve.
Iran J Child Neurol. 2023 Summer;17(3):157-162. doi: 10.22037/ijcn.v17i2.37749. Epub 2023 Jul 1.
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An isolated cavernous malformation of the sixth cranial nerve: A case report and review of literature.孤立性第六颅神经海绵状畸形:一例报告并文献复习。
Surg Neurol Int. 2021 Nov 16;12:563. doi: 10.25259/SNI_811_2021. eCollection 2021.
5
Acute Transient Oculomotor Nerve Palsy from Presumed Cavernous Angioma in an Infant.婴儿疑似海绵状血管瘤所致急性短暂性动眼神经麻痹
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脑池段三叉神经海绵状畸形
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4
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Neurocrit Care. 2011 Feb;14(1):84-5. doi: 10.1007/s12028-010-9455-x.
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Neurosurg Focus. 2010 Sep;29(3):E7. doi: 10.3171/2010.5.FOCUS10149.
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Nat Rev Neurol. 2009 Dec;5(12):659-70. doi: 10.1038/nrneurol.2009.177.
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