[The effect of estradiol on histamine distribution in the uterine structures of the normal rat and after the experimental administration of the hormone].

Estradiol levels were radioimmunoassayed and histamine levels histochemically measured by Cross', Ewen's, and Rost's methods in intact rats. Estradiol was shown to increase sharply the absorption of exogenous histamine by uterine structures. Estradiol effects were interpreted by the authors as activation of the histamine receptors in uterine structures by the hormone, and an estradiol-induced decrease in a histamine level in macrophages was explained by histamine release from macrophages for passing to other structures.