[Immunogenetic grounds for the development of local forms of primary tuberculosis in children].

The ++clinico-immunogenetic status of children with local forms of primary tuberculosis was analysed. Examination included 99 children aged 4-14 years with pulmonary tuberculosis. The control group comprised 51 children who has negative tuberculin tests and no intercurrent diseases. The HLA composition was determined by the A, B, C and DR loci. The HLA-DR2 representation is responsible for a high specific process risk and HLA-A11 and HLA-B15 can be characterized as antigens causing a resistance to tuberculosis infection.