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美国鼻科学会关于慢性鼻-鼻窦炎“最大程度药物治疗”的会员调查。

American Rhinologic Society member survey on "maximal medical therapy" for chronic rhinosinusitis.

作者信息

Dubin Marc G, Liu Cindy, Lin Sandra Y, Senior Brent A

机构信息

Department of Otolaryngology, Greater Baltimore Medical Center, Maryland, USA.

出版信息

Am J Rhinol. 2007 Jul-Aug;21(4):483-8. doi: 10.2500/ajr.2007.21.3047.

Abstract

BACKGROUND

"Maximal medical therapy" is the standard of care for chronic rhinosinusitis (CRS) treatment before the recommendation for surgery. However, this therapy is not consistent. Therefore, as a first step in determining the role of the disparate "maximal medical" treatments for CRS, American Rhinologic Society (ARS) members were surveyed.

METHODS

A survey was mailed to all nonresident members of the ARS (n=723). Focusing on the time period before surgical intervention is first considered for CRS patients, the survey assessed types of therapies, frequency of use, details on antibiotic and steroid usage, use of computed tomography (CT), and demographic data of respondents. All responses were anonymous.

RESULTS

Three hundred eight surveys were returned (43%). A majority of respondents used oral antibiotics and nasal steroids "almost always (>90%)". Oral antibiotics, oral steroids, nasal steroids, saline irrigation, and allergy testing were most commonly used at least "usually (50-90%)". The median antibiotic length was 3.1-4 weeks. The mean peak prednisone dose was 51.7 mg when oral steroids were used. Therapies that were rarely or never used by the majority included oral antifungals, antifungal spray, antibiotic spray, antibiotic nebulizer, steroid nebulizer, and i.v. antibiotics.

CONCLUSION

Oral antibiotics (median, 3.1-4 weeks) and nasal steroids are used >90% of the time by a majority of ARS members for maximal medical treatment of CRS.

摘要

背景

“最大程度药物治疗”是慢性鼻-鼻窦炎(CRS)手术推荐前的标准治疗方法。然而,这种治疗方法并不一致。因此,作为确定不同的CRS“最大程度药物”治疗作用的第一步,对美国鼻科学会(ARS)成员进行了调查。

方法

向所有ARS非驻地成员(n = 723)邮寄了一份调查问卷。该调查聚焦于首次考虑对CRS患者进行手术干预之前的时间段,评估了治疗类型、使用频率、抗生素和类固醇使用细节、计算机断层扫描(CT)的使用情况以及受访者的人口统计学数据。所有回复均为匿名。

结果

共收回308份调查问卷(43%)。大多数受访者“几乎总是(>90%)”使用口服抗生素和鼻用类固醇。口服抗生素、口服类固醇、鼻用类固醇、盐水冲洗和过敏测试最常至少“通常(50 - 90%)”使用。抗生素使用的中位时长为3.1 - 4周。使用口服类固醇时,泼尼松的平均峰值剂量为51.7毫克。大多数人很少或从不使用的治疗方法包括口服抗真菌药、抗真菌喷雾剂、抗生素喷雾剂、抗生素雾化器、类固醇雾化器和静脉用抗生素。

结论

大多数ARS成员在对CRS进行最大程度药物治疗时,90%以上的时间使用口服抗生素(中位时长3.1 - 4周)和鼻用类固醇。

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