Khapake Dinanath P, Jambhekar Nirmala A, Anchan Chetan, Madur Bhulaxmi P, Chinoy Roshni F, Agarwal M, Puri A
Department of Pathology, Tata Memorial Hospital, Parel, Mumbai.
Indian J Pathol Microbiol. 2007 Jul;50(3):563-5.
Epithelioid sarcomas (ES) are rare tumors of soft tissue that have a propensity to occur in the extremities. Epithelioid sarcomas are known to metastatise to draining lymph nodes and commonly to the lungs. Herein, a case of epithelioid sarcoma which recurred in an unusual site namely the distal phalanx of left middle finger, six months post amputation of the primary lesion in the left foot is being reported. The ipsilateral inguinal lymph node showed metastatic deposits. The tumor at both these sites had similar histology and an identical immunohistochemical (IHC) pattern showing reactivity to cytokeratin (CK), epithelial membrane antigen (EMA), vimentin (Vim) and CD34. This case is presented to record an unusual occurrence of ES in the distal phalanx of middle finger with an ES of foot. The metastasis of ES to the distal acral bones has not been documented till date.
上皮样肉瘤（ES）是一种罕见的软组织肿瘤，倾向于发生在四肢。已知上皮样肉瘤会转移至引流淋巴结，通常还会转移至肺部。在此，报告一例上皮样肉瘤病例，该病例在左脚原发性病变截肢六个月后，于一个不寻常的部位即左手中指远端指骨复发。同侧腹股沟淋巴结显示有转移灶。这两个部位的肿瘤具有相似的组织学特征和相同的免疫组化（IHC）模式，对细胞角蛋白（CK）、上皮膜抗原（EMA）、波形蛋白（Vim）和CD34呈阳性反应。本文呈现该病例以记录ES在中指远端指骨与足部ES同时出现的罕见情况。迄今为止，ES转移至远端手足骨尚未见文献记载。
